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Praziquantel More Info

Praziquantel is a synthetic heterocyclic compound, specifically an acylated quinoline-pyrazine isoindole derivative, identified by the CAS registration number 55268-74-1. It was developed in the 1970s following extensive antimicrobial research by German pharmaceutical companies Bayer and E. Merck. Its discovery marked a pivotal advancement in parasitology, as it presented a highly effective and broad-spectrum solution against a pervasive class of parasites with a previously favorable safety profile. The compound is a white to nearly white crystalline powder that is bitter tasting and insoluble in water. Its synthesis is a multi-step chemical process, and its unique structure is essential for its specific mechanism of action, which is distinct from older anthelmintic agents.

Uses and Applications

The primary and most critical application of praziquantel is in human and veterinary medicine as an anthelmintic agent. It is the World Health Organization's (WHO) drug of choice for treating infections caused by parasitic flatworms, specifically schistosomes (the causative agents of schistosomiasis, also known as bilharzia) and food-borne trematodes (such as liver flukes and lung flukes). Its efficacy stems from its ability to induce severe calcium ion influx and intense spasms in the worm's tegument, leading to paralysis, dislodgement, and subsequent death, which allows the host's immune system to clear the infection. In veterinary practice, it is extensively used in companion animal health products, particularly for the control of tapeworms in dogs and cats, and is also effective against certain cestode infections in livestock.

Application Market

The global market for praziquantel is substantial and is driven by its status as an essential medicine. A significant portion of its demand is fueled by large-scale public health initiatives orchestrated by the WHO and other global health bodies aimed at controlling and eliminating schistosomiasis, which affects hundreds of millions of people, primarily in tropical and subtropical regions of sub-Saharan Africa, South America, and Asia. The veterinary market represents another major segment, encompassing both prescription and over-the-counter formulations for pets, which is a stable and high-volume industry, especially in North America and Europe. Furthermore, its inclusion on the WHO's List of Essential Medicines ensures continuous production and distribution by multiple pharmaceutical manufacturers worldwide, making it a cornerstone of global health equity efforts.

Handling and Considerations

While praziquantel is considered safe for therapeutic use under medical supervision, appropriate handling precautions are necessary for the pure active pharmaceutical ingredient (API). Personal protective equipment, including gloves and safety glasses, is recommended to prevent potential irritation from dust exposure during handling. It is crucial to avoid inhalation of fine particles and to use adequate ventilation or respiratory protection in industrial settings where dust is generated. The compound should be stored in a tightly closed container in a cool, dry, and well-ventilated place, away from incompatible materials. From a clinical perspective, its use is generally contraindicated in patients with known hypersensitivity to the drug and requires careful evaluation in very young children or individuals with severe liver impairment. As with any pharmaceutical, it must be used strictly according to prescribed guidelines to ensure efficacy and safety.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.