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BEST CEFTIOFUR HYDROCHLORIDE ceftiofur hydrochloride

Name: BEST CEFTIOFUR HYDROCHLORIDE ceftiofur hydrochloride
Brand: JIU LONG
SKU: pr2511281540
Price: 95 USD
Availability: InStock

10 Inquiries

Unit Price: Get Latest Price 

CAS No.:

103980-44-5

Content:

99%

Port:

all chinese ports and airports

Brand:

JIU LONG

Packaging:

25kg/drum

Price valid (until):

2025-12-28

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Shandong Jiulong Veterinary APIs

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Tildipirosin,Tilmicosin Phosphate,Tilmicosin

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Ceftiofur Hydrochloride is a third-generation cephalosporin antibiotic exclusively developed for veterinary use, with strong antibacterial activity against Gram-negative bacteria and broad coverage of Gram-positive bacteria. As a water-soluble cephalosporin derivative, it is easy to process into sterile injectables (for severe individual infections) and water-soluble powders (for group prevention), making it a first-line drug for controlling bacterial infections in livestock and poultry.

Core Mechanism of Action: It exerts bactericidal effects by specifically binding to penicillin-binding proteins (PBPs) on bacterial cell membranes, inhibiting the synthesis of bacterial cell wall peptidoglycan. Unlike first/second-generation cephalosporins, it has stronger stability against bacterial beta-lactamases (enzymes that inactivate antibiotics), so it is effective against beta-lactamase-producing strains. Its antibacterial spectrum mainly covers:

Gram-negative bacteria: Haemophilus parasuis (swine Glässer's disease), Pasteurella multocida (bovine pasteurellosis, swine pasteurellosis), Escherichia coli (poultry colibacillosis, swine colibacillosis), Actinobacillus pleuropneumoniae (swine pleuropneumonia);
Gram-positive bacteria: Streptococcus suis (swine streptococcosis), Staphylococcus aureus (bovine mastitis, swine skin abscesses);
Other pathogens: Salmonella spp. (poultry pullorum disease, swine salmonellosis).

Main Application Scenarios:

Swine:
- Piglets (3-7 days old): Prevent and treat neonatal colibacillosis (yellow/white diarrhea) via intramuscular injection;
- Growing-finishing pigs: Treat bacterial respiratory diseases (pleuropneumonia, Glässer's disease) with injectables, and prevent group infections with water-soluble powders mixed in drinking water;
- Sows: Treat postpartum metritis-mastitis-agalactia syndrome (MMA) via intramuscular injection, reducing sow mortality and improving litter survival rate.
Cattle & Sheep:
- Beef cattle: Treat pasteurellosis (fever, dyspnea) and foot rot (caused by Fusobacterium necrophorum) via injection;
- Dairy cows: Treat acute mastitis (caused by Staphylococcus aureus, Streptococcus agalactiae) via intramammary infusion, without affecting milk quality (complies with residue limits).
Poultry (Chickens, Ducks):
- Broilers: Treat colibacillosis (air sacculitis, pericarditis) and salmonellosis (pullorum disease) via drinking water, reducing mortality;
- Layer hens: Prevent bacterial infections during peak egg production, avoiding egg drop caused by infections.

Product Advantages:

Strong antibacterial activity: Effective against beta-lactamase-producing strains (resistant to first/second-generation cephalosporins), solving the problem of antibiotic resistance in intensive breeding;
Long-lasting efficacy: The elimination half-life is 8-12 hours in swine and 6-8 hours in cattle, requiring only 1 injection every 24 hours (or 1 drinking water administration per day), reducing labor costs;
High safety: Low toxicity to target animals; no obvious irritation to injection sites (sterile grade); no teratogenic/mutagenic effects at recommended dosages; complies with international veterinary drug residue limits (EU MRLs, US FDA CVM standards), with no residue risks in meat, milk, or eggs;
Flexible formulation: Ordinary grade is suitable for group prevention (water-soluble powders/pre-mixes); sterile grade meets the requirements of injectables for severe cases, adapting to different breeding scales and infection degrees;
Reliable quality:
- Ordinary grade: Produced in GMP workshops, with strict detection of purity, moisture, and related substances;
- Sterile grade: Manufactured in Class 100 sterile production areas, with 100% batch testing of sterility and bacterial endotoxins; each batch is accompanied by a Certificate of Analysis (COA) for full quality traceability.

This product is widely used in global intensive livestock and poultry breeding industries, especially in large-scale farms with high requirements for antibiotic efficacy and safety, and is an essential raw material for veterinary drug manufacturers to produce high-quality third-generation cephalosporin preparations.

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Basic Info

Product Name:

Ceftiofur hydrochloride

Other Name:

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-,hydrochloride (1:1),(6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-,monohydrochloride,[6R-[6α,7β(Z)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-,monohydrochloride,(6R,7R)-;Ceftiofur hydrochloride;U 64279A;Excenel;U 67279A;Excenel RTU;Spectramast LC;Aviar;Cefalus

CAS No.:

103980-44-5

Molecular Formula:

C19H17N5O7S3.ClH

InChIKeys:

InChIKey=KEQFDTJEEQKVLM-JUODUXDSSA-N

Molecular Weight:

560.02

Exact Mass:

559.005676

EC Number:

1312995-182-4

UNII:

6822A07436

NCI Thesaurus Code:

C76174

HScode:

2941905990

Categories:

Veterinary Raw Materials

Characteristics

PSA:

256 Å²

XLogP3:

2.69300

Appearance:

off-white solid

Melting Point:

>190°C (dec.)

Boiling Point:

814.1°C at 760 mmHg

Flash Point:

446.1ºC

Storage Conditions:

-20°C Freezer

Vapor Pressure:

5.14E-28mmHg at 25°C

See More Ceftiofur hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Skin sensitization, Sub-category 1B

Respiratory sensitization, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H317 May cause an allergic skin reaction H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Prevention	P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P284 [In case of inadequate ventilation] wear respiratory protection.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Ceftiofur hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Tildipirosin,Tilmicosin Phosphate,Tilmicosin

Location:
Yinfeng International Biopark, No.1177 Chunlan Road, High-tech district, Jinan City, Shandong Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
365

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
101-200

Year of Establishment:
2008

Certifications:
GMP

Company Profile

Inquiry History

10 Inquiries

Country	Product	Purchase Quantity	Date Posted
Paraguay	Ceftiofur hcl	25.00 KG	Dec 1, 2025
Ecuador	CEFTIOFUR CLORHIDRATO	40 KG	Feb 6, 2025
Paraguay	Flunixin meglumine	75 KG	Jan 23, 2026
Paraguay	Almidon pre-gelatinizado	300.00 KG	Dec 1, 2025
Paraguay	Dichloromethane	5000.00 KG	Dec 1, 2025
Paraguay	Vitamin B12	3.00 KG	Dec 1, 2025
Paraguay	Ricini oluem Aceite de ricino	1600 KG	Dec 1, 2025
Paraguay	Pyrantel pamoate	75.00 KG	Dec 1, 2025
Paraguay	Azepromacine maleate	12.00 KG	Dec 1, 2025
Paraguay	D.D.V.P.technical	16000.00 KG	Dec 1, 2025

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