Name | Poly(L-lactic acid) |
CAS number | 26811-96-1 |
Description | D-Mannitol is a naturally occurring sugar alcohol, classified as a hexitol, with the CAS Registry Number 69-65-8. Its molecular structure is the reduced form of the sugar mannose, featuring six carbon atoms each bearing a hydroxyl group, making it a stereoisomer of sorbitol. |
Structural formula |  |
Molecular Formula | (C3H6O3)m |
Molecular Weight | 90.07 g/mol |
Appearance | White powder |
Quality Standard | 99% |
Storage Condition | Cool dry place( away from the light) |
Shelf Life | >2 years if stored properly |
Sample package | Aluminium foil bag |
Commercial package | Aluminium Tin, Fiber drum |
Origin | China |
Poly(L-lactic acid) More Info
Poly(L-lactic acid) is a biodegradable and biocompatible thermoplastic polyester derived from renewable resources, assigned the CAS Registry Number 26811-96-1. Its polymer chain consists of repeating monomeric units of L-lactic acid, linked by ester bonds. This specific stereochemical configuration, as opposed to its D- or racemic counterparts, is crucial for its crystalline properties, degradation profile, and mechanical strength. It is typically produced via the ring-opening polymerization of L-lactide, resulting in a material that can range from amorphous to semi-crystalline depending on its molecular weight and processing history.
The defining characteristics of this polymer are its biodegradability and bioresorbability within the human body. Its degradation occurs primarily through hydrolysis of the ester linkages in the polymer backbone, breaking the long chains into shorter fragments. These oligomers and eventually lactic acid monomers are then metabolized via the Krebs cycle to carbon dioxide and water. The rate of this process can be engineered from months to years by controlling factors such as crystallinity, molecular weight, and the physical form of the implant.
The applications of Poly(L-lactic acid) are extensive and significant in the biomedical and environmental fields. In medicine, it is a foundational material for bioresorbable surgical sutures, orthopedic fixation devices like screws and pins, and scaffolds for tissue engineering. Its ability to provide temporary mechanical support and then gradually disappear as the body heals eliminates the need for a second surgery for hardware removal. Commercially, it is a leading bioplastic used in packaging, disposable utensils, and fibers, offering a renewable alternative to petroleum-based plastics.
From a material science perspective, the properties of Poly(L-lactic acid) can be finely tuned. While it possesses good mechanical strength and rigidity, it is often blended with other polymers like poly(glycolic acid) or plasticized to modify its brittleness, flexibility, and degradation rate. Its processing is compatible with standard industrial techniques such as injection molding, extrusion, and 3D printing, allowing for the cost-effective manufacture of complex shapes and devices tailored to specific applications.
The safety and regulatory profile of Poly(L-lactic acid) is excellent, underpinning its widespread use. As its degradation products are natural metabolites, it is highly biocompatible and generally evokes a minimal inflammatory response, which is typically a mild, transient foreign-body reaction. It has received regulatory approvals from major agencies worldwide for use in numerous medical devices and food-contact applications. Its production from annually renewable resources like corn starch or sugarcane also positions it as a key material in the development of a more sustainable and circular economy.
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