99% Diclofenac Sodium Pharmaceutical Grade White Raw Power With Best Price and Fast Delivery

Diclofenac Sodium More Info

Diclofenac Sodium is a non-steroidal anti-inflammatory drug of the phenylacetic acid class, designated with the CAS Registry Number 15307-79-6. Its molecular structure consists of two aromatic rings linked by an amino group, which is further connected to an acetic acid moiety. The sodium salt formulation enhances its water solubility and stability for pharmaceutical use. This specific chemical architecture is optimized for potent inhibition of cyclooxygenase enzymes, the key mediators of inflammation and pain.

The primary mechanism of action for diclofenac is the non-selective, reversible inhibition of cyclooxygenase enzymes, specifically COX-1 and COX-2. By binding to the active site of these enzymes, it prevents the conversion of arachidonic acid into prostaglandin precursors. Prostaglandins are critical signaling molecules that promote inflammation, pain, and fever. Through this inhibition, diclofenac effectively reduces these symptoms. It also demonstrates a preferential affinity for COX-2 in clinical settings and may have additional effects on arachidonic acid release and lipoxygenase pathways.

Diclofenac is indicated for the treatment of a wide variety of acute and chronic inflammatory and painful conditions. Its major uses include the management of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute musculoskeletal injuries such as sprains, and postoperative pain. It is also highly effective in treating acute gout attacks and is available in ophthalmic solutions to reduce inflammation following cataract surgery and in topical formulations for localized pain relief.

This drug is available in numerous formulations designed for different therapeutic needs and routes of administration. These include immediate-release and enteric-coated oral tablets, sustained-release capsules, solutions for intramuscular injection, suppositories, transdermal patches, gels, and ophthalmic drops. The diversity of formulations allows for tailored therapy, from rapid systemic effect to targeted local action with minimized systemic exposure, catering to specific patient conditions and preferences.

The safety profile of diclofenac includes well-documented risks common to traditional NSAIDs. The most frequent adverse effects are gastrointestinal, such as dyspepsia, nausea, and abdominal pain, with a significant risk of serious ulcers and bleeding. It carries notable risks of cardiovascular events, including an increased potential for myocardial infarction and stroke, particularly with long-term, high-dose use. Additional concerns include renal impairment, elevated liver enzymes, and, rarely, severe skin reactions. These risks necessitate using the lowest effective dose for the shortest possible duration under appropriate medical supervision.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.