 Home > Food Additives > Nutrition Supplements > (±)-Lipoic acid for Sale > Alpha Lipoic Acid (ALA) 99% CAS:1077-28-7 | High Purity Antioxidant Raw Material | GMP Factory for Pharma & Supplement Use

Alpha Lipoic Acid (ALA) 99% CAS:1077-28-7 | High Purity Antioxidant Raw Material | GMP Factory for Pharma & Supplement Use buy - large image1

Alpha Lipoic Acid (ALA) 99% CAS:1077-28-7 | High Purity Antioxidant Raw Material | GMP Factory for Pharma & Supplement Use buy - image1

Alpha Lipoic Acid (ALA) 99% CAS:1077-28-7 | High Purity Antioxidant Raw Material | GMP Factory for Pharma & Supplement Use buy - image2

Alpha Lipoic Acid (ALA) 99% CAS:1077-28-7 | High Purity Antioxidant Raw Material | GMP Factory for Pharma & Supplement Use buy - image3

Alpha Lipoic Acid (ALA) 99% CAS:1077-28-7 | High Purity Antioxidant Raw Material | GMP Factory for Pharma & Supplement Use buy - image4

Alpha Lipoic Acid (ALA) 99% CAS:1077-28-7 | High Purity Antioxidant Raw Material | GMP Factory for Pharma & Supplement Use

Name: Alpha Lipoic Acid (ALA) 99% CAS:1077-28-7 | High Purity Antioxidant Raw Material | GMP Factory for Pharma & Supplement Use
Brand: HyperChem
SKU: pr2604162326
Price: 120 USD
Availability: InStock

TDS 14 Inquiries

Unit Price:

$120-150/KG FOB

Get Latest Price 

CAS No.:

1077-28-7

Grade:

Pharmaceutical Grade

Content:

99.9%

Port:

Hangzhou

Brand:

HyperChem

Packaging:

1g/bag, 20g/bag, 50g/bags or other quantities

Price valid (until):

2028-05-31

Contact Supplier

 Chat Now

Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Name	Alpha Lipoic Acid
CAS number	1077-28-7
Synonym	thioctic acid alpha-Lipoic acid alpha Lipoic Acid 6,8-Thioctic acid
Related APIs #	N-Acetylcysteine Coenzyme Q10 Acetyl-L-Carnitine Glutathione L-Carnitine Dihydrolipoic Acid S-Adenosylmethionine Quercetin Benfotiamine R-Lipoic Acid
Description	Mechanism of Action Ritlecitinib functions by covalently binding to a specific cysteine residue (Cys-909) in JAK3, which is crucial for cytokine signaling involved in immune responses. This selective inhibition is significant because it minimizes off-target effects that are common with less selective JAK inhibitors. Applications 1. Treatment of Alopecia Areata In June 2023, Ritlecitinib was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents aged 12 years and older. This condition is characterized by sudden hair loss and is believed to be an autoimmune disorder. The drug's ability to inhibit JAK3 helps modulate the immune response that contributes to hair follicle destruction. 2. Potential for Other Autoimmune Conditions Given its mechanism of action, Ritlecitinib may have potential applications in treating other autoimmune diseases where cytokine signaling plays a critical role, although further studies are needed to establish efficacy in these areas. Alpha Lipoic Acid (ALA) is a naturally occurring compound notable for its powerful antioxidant properties and its role as a cofactor in mitochondrial energy metabolism. It is unique due to its capability to operate in both aqueous and lipid environments, making it exceedingly versatile compared to other antioxidants. Herein, we'll explore the mechanism of action of ALA, its applications, benefits, and future development without touching upon sensitive topics or terminologies. Mechanism of Action Alpha Lipoic Acid functions primarily as a cofactor for vital mitochondrial enzyme complexes, thereby playing a significant role in the citric acid cycle. This cycle is essential for generating adenosine triphosphate (ATP), the energy currency in biological systems. Additionally, ALA is an efficient antioxidant. Unlike typical antioxidants, it is notable for its ability to scavenge reactive oxygen species in both its oxidized and reduced forms. The reduced form, dihydrolipoic acid (DHLA), is particularly robust, capable of regenerating other antioxidants such as glutathione, Vitamin C, and Vitamin E, thus amplifying their cumulative antioxidative effects. Further distinguishing ALA is its role in modulating signaling pathways related to inflammation and oxidative stress. This modulation is crucial for maintaining cellular homeostasis and protecting cells from damage over time. Applications The biochemical properties of ALA have led to its application in numerous areas concerning human health. One significant application lies in its ability to support the health of the neurological system. Given its ability to cross the blood-brain barrier, ALA is particularly relevant in supporting nerve health and maintaining optimal cognitive function. Its antioxidative prowess is crucial in protecting nerve cells from oxidative stress, which is a contributing factor in the decline of cognitive abilities. Another important application is in the area of energy metabolism. Given its necessity in the mitochondrial energy production process, ALA is often utilized to enhance energy levels and combat feelings of fatigue, particularly in older individuals where natural ALA levels may diminish. Furthermore, ALA's role in reducing oxidative stress makes it a potential agent for supporting overall cellular health—contributing to skin health by mitigating damage caused by environmental stressors like UV radiation. Usefulness The versatility of Alpha Lipoic Acid extends across various health aspects due to its systemic involvement in crucial physiological processes. Its potential to reduce oxidative damage contributes significantly to overall health, particularly in the context of aging—where oxidative stress is a known factor. By bolstering the body's antioxidant defenses, ALA may support longevity and vitality. Moreover, ALA's capacity to interact with and enhance the function of other antioxidants makes it exceptionally effective in comprehensive cellular protection strategies. This synergistic property is highly valued in dietary supplements formulated to support overall health maintenance. Development Prospects Looking to the future, the prospects for Alpha Lipoic Acid are promising, with ongoing research likely to uncover more of its capabilities and potential applications. As interest in nutritional and supplemental science grows, driven by a global aging population and the rising prevalence of lifestyle-related health concerns, the demand for potent dietary supplements like ALA is expected to increase. Scientific exploration is focused on further elucidating the biochemical pathways influenced by ALA beyond its antioxidant roles, such as its potential impact on gene expression related to inflammation and metabolic health. Research is also investigating its synergistic potentials when combined with other nutrient compounds to optimize health outcomes. Consumer interest is also likely to grow, driven by an increase in self-care awareness and preventive health measures. ALA's established role in promoting healthy aging, supporting neuroprotection, and enhancing energy production is likely to attract a broad spectrum of the population, from individuals seeking holistic wellness solutions to those looking to support specific health goals. In the sphere of product development, Alpha Lipoic Acid is positioned well for integration into a variety of health supplements and functional foods. Its stability when properly formulated and its compatibility with a range of delivery systems enhance its desirability for both manufacturers and consumers. In conclusion, Alpha Lipoic Acid stands as an exemplary compound with multifaceted health benefits, rooted in its profound biochemical functions and antioxidant capability. The continued interest in its properties promises to yield new insights and applications, fortifying its status as a cornerstone of health and wellness strategies in the coming years.
Molecular Formula	C ₈ H ₁₄ O ₂ S ₂
Molecular Weight	206.3 g/mol
Appearance	White or almost white powder
Quality Standard	Enterprise standard; 99.99%
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 0-28℃ for short term (days to weeks) or 0-8 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Double plastic bags inside, fiber drum outside, any quantity available.
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Shop USP Quality Standard API Finasteride Powder with CAS 98319-26-7-Detailed Image 2

Shop USP Quality Standard API Finasteride Powder with CAS 98319-26-7-Detailed Image 3

FAQ

Q1. What is the Hyper chem payment term?
T/T advance
LC at sight
DP at sight
Trade assurance
Money gram

Q2. What is Hyper chem shipment policy?
Our policy is to strive for the quickest shipment time possible, with ready stock sample shipment typically going out the same day that your order was placed. Your satisfaction is very important to us.
For non-ready stock, please contact the Hyper Chem sales team to negotiate.

Q3. What hyper chem will provide after shipment?
For sample orders:
After shipment is done, an timely email including:

Track details (Fedex /TNT/DHL/EMS Track number)

Package photo

COA, MSDS, etc

Dispatch date & Estimated arriving time

Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided
in scan-copy and original, to help customers complete the customs clearance process.

Q4. What is Hyper Chem shipment term?

By Express
DHL  FedEx  TNT  EMS
Fast:5 days around
High cost, door to door service

By Air
Suitable for more than 50kg
Fast :3-7 days Hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Slow:7-45 days, Low cost, port to port, professional broker needed
We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. Does hyper chem provide a shipment return policy?
Yes, we have.
Return Policy: At Hyper chem, your satisfaction is guaranteed. If you are dissatisfied for any reason with a product, please send back the unused portion along with your packing slip and a brief note on why you were dissatisfied within 45 days of purchase for a full refund to:

Q6. What is hyper chem After-sales service
•Documents support: COA ,MSDS, MOA ,MS Report,HNMR Report,SDS,DMF
• Customer Support: Shipment clearance support, quality issue support
• Automated Customer Service: Our worldwide customers enjoy immediate 24/7 access to the HYPER CHEM support team from any location, at any time.

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

Certificates

Basic Info

Product Name:

(±)-Lipoic acid

Other Name:

1,2-Dithiolane-3-pentanoic acid;1,2-Dithiolane-3-valeric acid,(±)-;1,2-Dithiolane-3-pentanoic acid,(±)-;dl-Thioctic acid;DL-α-Lipoic acid;DL-6-Thioctic acid;DL-6,8-Thioctic acid;(±)-Thioctic acid;(±)-α-Lipoic acid;DL-Thioctic acid;(RS)-Lipoic acid;(RS)-α-Lipoic acid;5-(1,2-Dithiolan-3-yl)pentanoic acid;5-(1,2-Dithiolan-3-yl)valeric acid;Protogen A;Pyruvate oxidation factor;Thioctacid;Thioctic acid;6,8-Thioctic acid;Tioctidasi;Tioctidasi acetate replacing factor;1,2-Dithiolane-3-valeric acid;6-Thioctic acid;α-Liponic acid;Tioctacid;Biletan;Thioctsan;Liposan;Lipothion;(±)-Lipoic acid;NSC 628502;dl-Lipoic acid;NSC 90788;Alipure;Espa-lipon;Thiotacid;dl-α-Lipoic acid;α-lipon 300;α-(±)-Lipoic acid;DL-Lipoic acid;Byodinoral-R;Octolipen;Oktolipen;62-46-4;27779-68-6

CAS No.:

1077-28-7

Molecular Formula:

C8H14O2S2

InChIKeys:

InChIKey=AGBQKNBQESQNJD-UHFFFAOYSA-N

Molecular Weight:

206.32600

Exact Mass:

206.33

EC Number:

200-534-6

NSC Number:

758651|90788

DSSTox ID:

DTXSID7025508

Color/Form:

Forms yellowish flakes

ATC Code:

A - Alimentary tract and metabolism

HScode:

2934999090

Categories:

Nutrition Supplements

Characteristics

PSA:

87.90000

XLogP3:

2.78510

Appearance:

light yellow to yellow powder

Density:

1.218g/cm3

Melting Point:

60-61 °C

Boiling Point:

160-165 °C

Flash Point:

173ºC

Refractive Index:

1.562

Water Solubility:

ethanol: 50 mg/mL | 0.9 g/L (20 ºC);In water, 127 mg/L at 25 deg C (est)

Storage Conditions:

2-8ºC

Vapor Pressure:

9.49X10-1 mm Hg at 25 deg C (est)

Henrys Law Constant:

Henry's Law constant = 1.64X10-8 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa = 5.10|pKa = 4.70 (carboxy) (est)

Collision Cross Section:

133.8 Å² [M+H-H2O]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]

Experimental Properties:

White powder, soluble in water, pH of aqueous solutions about 7.4 /Thioctic acid, sodium salt/|Crystals by vacuum sublimation (at 85-90 °C and 25 micron). MP: 46-48 °C (microblock). Specific optical rotation: + 104 deg at 23 °C/D (c = 0.88 in benzene). UV max (methanol): 333 nm (epsilon 150). pKa = 5.4. Practically insoluble in water. Soluble in fat solvents. /Thioctic acid, d-form/|Yellow needles from cyclohexane. MP: 60-61 °C. BP: 160-165 °C. Practically insoluble in water; soluble in fat solvents. Forms a water-soluble sodium salt. /Thioctic acid, dl-form/|Crystals from cyclohexane. MP: 45-47.5 °C (microblock). Specific optical rotation: -113 deg at 23 °C/D (c = 1.88 in benzene). UV max (methanol): 330 nm (epsilon 140). /Thioctic acid, l-form/|Hydroxyl radical reaction rate constant = 2.52X10-10 cu m/molec-sec at 25 °C (est)

See More (±)-Lipoic acid Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Skin sensitization, Category 1

Eye irritation, Category 2

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H411 Toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store in tight container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity.

See More (±)-Lipoic acid Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

14 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	DL-Thioctic acid	25 KG	Jan 6, 2025
India	Alpha Lipoic Acid	1.00 MT	Jun 29, 2026
Brazil	Alpha L Acid	1 KG	Apr 16, 2026
Turkey	Thioctic Acid	600 MG	Feb 25, 2025
Thailand	Alpha Lipoic Acid	1 KG	Jan 22, 2025
Egypt	alpha lipoic acid	2 MT	Jul 21, 2024
Egypt	Thioctic acid 99% Yellow powder	500 KG	Oct 18, 2023
Turkey	Factory Price Alpha Lipoic Acid ALA 99% from China	200 KG	Aug 2, 2023
Egypt	Alpha Lipoic Acid Powder	200.00 KG	Feb 24, 2025
India	Alpha Lipoic Acid	300 KG	Dec 26, 2024
India	Alpha Lipoic Acid	5000 KG	Dec 20, 2024
India	ALPHA LIPOIC ACID	200 KG	Nov 22, 2024
India	Factory Price Alpha Lipoic Acid ALA 99% from China	500 MT	Oct 22, 2023
India	Alpha Lipoic Acid	500.00 KG	Jun 28, 2024

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Supplier Name	Details
Hot sale Alpha Lipoic acid	Cosmetics Grade/99.9	Shandong Taigeng Chemical Co.,LTD.	Inquiry
China Largest factory Manufacturer Supply Alpha Lipoic Acid CAS 1077-28-7	Pharmaceutical Grade/99	LEADER BIOCHEMICAL GROUP	Inquiry
DL-Alpha-Lipoic Acid	Pharmaceutical Grade/99	GIHI CHEMICALS CO.,LIMITED	Inquiry
Alpha Lipoic Acid / α-Lipoic Acid SNC \| Good Fortune	Food Grade/99	SNC \| GOOD FORTUNE	Inquiry
alpha lipoic acid 1077-28-7	/	Sinoway Industrial Co., Ltd.	Inquiry

Alpha Lipoic Acid (ALA) 99% CAS:1077-28-7 | High Purity Antioxidant Raw Material | GMP Factory for Pharma & Supplement Use

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

Related Products

More Choices Find All Products for Sale 

Related Searches

Hot Related Products