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Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.

In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.

The beauty effect of GHK-Cu /Blue Copper peptide:Stimulate the formation of collagen and elastin, firm the skin and reduce fine lines.
Restore skin repair ability, increase the production of skin cell mucus, and reduce skin damage.
Stimulate the formation of glucosamine, increase the thickness of the skin, and reduce the looseness and firmness of the skin.
Promote blood vessel proliferation and increase skin oxygen supply.The auxiliary antioxidant enzyme SOD has a strong and beneficial anti-free radical function.
Expanding hair follicles accelerates hair growth and inhibits hair loss.
Stimulate the production of melanin in hair,
regulate the energy metabolism of hair follicle cells, remove free radicals on the skin, and inhibit the active function of
stimulating 5-α reduction enzymes.