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Sebacic acid111-20-6C10H18O4

Name: Sebacic acid111-20-6C10H18O4
Brand: OORENT
SKU: pr2608261543
Price: 33 USD
Availability: InStock

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CAS No.:

111-20-6

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

shanghai

Brand:

OORENT

Packaging:

Vial/Bottle/Bag/Carton

Price valid (until):

2027-11-16

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Qingdao Orient Chemical Co.,LTD

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Product Description
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Inquiry History

Description

Product Detail

Sebacic acid Basic information

The main method of preparation Chemical properties Uses Production method Toxicity Hazards & Safety Information

Product Name:	Sebacic acid
Synonyms:	RARECHEM AL BO 0380;SEBACIC ACID;1,10-decanedioicacid;acidesebacique;Ipomic acid;n-Decanedioic acid;n-decanedioicacid;1,8-OctanedicarbozylicAcid
CAS:	111-20-6
MF:	C10H18O4
MW:	202.25
EINECS:	203-845-5
Product Categories:	alpha,omega-Alkanedicarboxylic Acids;alpha,omega-Bifunctional Alkanes;Monofunctional & alpha,omega-Bifunctional Alkanes;Organic Chemicals;Intermediates;Cosmetics;bc0001;111-20-6
Mol File:	111-20-6.mol

Sebacic acid Chemical Properties

Melting point	133-137 °C (lit.)
Boiling point	294.5 °C/100 mmHg (lit.)
density	1.21
bulk density	600-620kg/m3
vapor pressure	1 mm Hg ( 183 °C)
refractive index	1.422
Fp	220 °C
storage temp.	Store below +30°C.
solubility	ethanol: 100 mg/mL
form	Powder or Granules
pka	4.59, 5.59(at 25℃)
color	White to off-white
Odor	monoclinic prismatic tablets, wh. powd., fatty acid odor
Water Solubility	1 g/L (20 ºC)
Merck	14,8415
BRN	1210591
Henry's Law Constant	7.6×10⁷ mol/(m³Pa) at 25℃, Compernolle and Müller (2014)
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents, bases, reducing agents.
Cosmetics Ingredients Functions	BUFFERING
InChI	1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14)
InChIKey	CXMXRPHRNRROMY-UHFFFAOYSA-N
SMILES	OC(=O)CCCCCCCCC(O)=O
LogP	1.5 at 23℃
CAS DataBase Reference	111-20-6(CAS DataBase Reference)
NIST Chemistry Reference	Decanedioic acid(111-20-6)
EPA Substance Registry System	Sebacic acid (111-20-6)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-24/25
WGK Germany	1
RTECS	VS0875000
TSCA	TSCA listed
HS Code	29171310
Storage Class	11 - Combustible Solids
Toxicity	LD50 orally in Rabbit: 3400 - 14500 mg/kg LD50 dermal Rat > 2000 mg/kg

MSDS Information

Provider	Language
Sebacic acid	English
SigmaAldrich	English
ACROS	English
ALFA	English

Sebacic acid Usage And Synthesis

The main method of preparation	(1) Castor oil is as raw material, ricinoleate is separated from castor oil, with the condition of inflating and 280~300℃, caustic soda proceeds alkali fusion and the reaction is heated for 10h, sebum acid sodium salt can obtain, deputy product is 2-octanol. The sodium salt is dissolved in water, adding sulfuric acid to neutralize, after bleaching, the solution is cooled to precipitate sebum acid, it is washed with cold water, and finally recrystallized. CH3 (CH2) 5CH (OH) CH2CH = CH (CH2) 7COOH + 2NaOH → CH3 (CH2) 5CH (OH) CH3 + NaOOC (CH2) 8COONa + H2 NaOOC (CH2) 3COONa + H2SO4 → HOOC (CH2) 8COOH + Na2SO4 (2) Adipic acid (hexane diacid) is as raw material to synthesize. Adipic acid and methanol can proceed esterification reaction to form dimethyl adipate, ion exchange membrane proceeds electrolytic oxidation to get dimer, i.e., dimethyl sebacate, and then reacts with sodium hydroxide to form the disodium salt, hydrochloric acid (or sulfuric acid) is used to neutralize and Sebacic acid can obtain. Chemical properties, uses and methods of preparation of sebacic acid are edited by Chemicalbook andy.（2016-12-04）
Chemical properties	It is white flaky crystal. It is slightly soluble in water, soluble in alcohol and ether.
Uses	Sebacic acid is widely used in the preparation of sebacic acid esters, such as dibutyl sebacate, dioctyl sebacate, diisooctyl sebacate. These esters can be used as plasticizers for plastics and cold-resistant rubber, as well as for polyamide, polyurethane, alkyd resin, synthetic lubricating oil, lubricating oil additives, spices, coatings, cosmetics, etc. It can also be used as raw material for producing nylon 1010, nylon 910, nylon 810, nylon 610, nylon 9 and high temperature resistant lubricating oil diethylhexyl ester. It is also the raw material for the production of alkyd resins (used as surface coatings, plasticized nitrocellulose coatings, and urea resin varnishes) and polyurethane rubber, cellulose resins, vinyl resins, and synthetic rubber plasticizers, softeners, and solvents.
Production method	Almost all of the current industrial production of sebacic acid is using castor oil as raw material. Castor oil cracking method: castor oil is heated under the action of alkali hydrolysis to generate ricinoleic acid sodium soap, and then add sulfuric acid acid to generate ricinoleic acid; in the presence of diluent cresol, add alkali heated to 260-280 ℃ for cracking to generate sebacic acid double sodium salt and secoctanol and hydrogen, cracked material diluted by water, heated and neutralized with acid, the double sodium salt into a monosodium salt; and then boiled with acid after decolorization of activated carbon neutralization solution. The monosodium salt of sebacic acid is turned into sebacic acid crystals, and then separated and dried to obtain the finished product.
Toxicity	Sebacic acid, also known as 1, 10-decanedioic acid, belongs to aliphatic dibasic acid. Sebacic acid was present in the leaves of flue-cured tobacco, burley tobacco and aromatic tobacco. Sebacic acid was white crystal in flake form at room temperature. Slightly soluble in water, sebacic acid was insoluble in benzene, petroleum ether, carbon tetrachloride. In contrast, sebacic acid was soluble in ethanol and ethyl ether. Irritant to the eyes, respiratory system and skin irritation, sebacic acid oral harmful. However, sebacic acid was low toxic and flammable.
Hazards & Safety Information	Category: Flammable liquid Toxicity: grading toxicity Acute oral toxicity-rat LD50: 14375 mg/kg; Oral-Mouse LD50: 6000 mg/kg Flammability hazard characteristics: flammable, the fire discharges acrid smoke Storage characteristics: Treasury ventilation low-temperature drying Extinguishing agent: Dry powder, foam, sand, water
Description	Sebacic acid is a dicarboxylic acid with structure (HOOC)(CH₂)₈(COOH), and is naturally occurring. In its pure state it is a white flake or powdered crystal. The product is described as non-hazardous, though in its powdered form it can be prone to flash ignition (a typical risk in handling fine organic powders). Sebaceus is Latin for tallow candle, sebum (tallow) is Latin for tallow, and refers to its use in the manufacture of candles. Sebacic acid is a derivative of castor oil, with the vast majority of world production occurring in China which annually exports over 20,000 metric tonnes, representing over 90 % of global trade of the product. In the industrial setting, sebacic acid and its homologues such as azelaic acid can be used in plasticizers, lubricants, hydraulic fluids, cosmetics, candles, etc. Sebacic acid is also used as an intermediate for aromatics, antiseptics, and painting materials.
Chemical Properties	White flaky crystals. Slightly soluble in water, soluble in alcohol and ether.
Uses	Sebacic Acid is a urinary metabolite that has been identified as an anti-fatigue biomarker.
Uses	Decanedioic acid was named by Thenard LJ (1802) from the Latin sebaceus(tallow candle) or sebum (tallow) in reference to its use in the manufacture of candles. Thenard LJ isolated this compound from distillation products of beef tallow. In 1954, it was reported that it was produced in excess of 10,000 tons annually by alkali fission of castor oil. Sebacic acid and its derivatives, as azelaic acid, have a variety of industrial uses as plasticizers, lubricants, diffusion pump oils, cosmetics, candles, etc. It is also used in the synthesis of polyamide, as nylon, and of alkyd resins. An isomer, isosebacic acid, has several applications in the manufacture of vinyl resin plasticizers, extrusion plastics, adhesives, ester lubricants, polyesters, polyurethane resins and synthetic rubber.
Preparation	Sebacic acid is normally made from castor oil, which is essentially glycerol triricinoleate. The castor oil is heated with sodium hydroxide at about 250e. This treatment results in saponification of the castor oil to ricinoleic acid which is then cleaved to give 2-octanol and sebacic acid: This process results in low yields of sebacic acid (about 50% based on the castor oil) but, nevertheless, other routes have not proved competitive. Sebacic acid is a colourless crystalline solid, m.p. 134.
Definition	ChEBI: Sebacic acid is an alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. It has a role as a human metabolite and a plant metabolite. It is an alpha,omega-dicarboxylic acid and a dicarboxylic fatty acid. It is a conjugate acid of a sebacate(2-) and a sebacate. It derives from a hydride of a decane.
General Description	White granular powder. Melting point 153°F. Slightly soluble in water. Sublimes slowly at 750 mm Hg when heated to melting point.
Air & Water Reactions	Insoluble in water.
Reactivity Profile	Sebacic acid reacts exothermically to neutralize bases, both organic and inorganic. May react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Can react with active metals to form gaseous hydrogen and a metal salt. Such reactions are slow in the dry, but systems may absorb enough water from the air to allow corrosion of iron, steel, and aluminum parts and containers. Reacts slowly with cyanide salts to generate gaseous hydrogen cyanide. Reacts with solutions of cyanides to cause the release of gaseous hydrogen cyanide. May generate flammable and/or toxic gases and heat with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. May react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Can be oxidized exothermically by strong oxidizing agents and reduced by strong reducing agents. May initiate polymerization reactions.
Fire Hazard	Flash point data for Sebacic acid are not available. Sebacic acid is probably combustible.
Flammability and Explosibility	Not classified
Purification Methods	Purify sebacic acid via the disodium salt which, after crystallisation from boiling water (charcoal), is again converted to the free acid. The free acid is crystallised repeatedly from hot distilled water or from Me2CO/pet ether and dried under vacuum. [Beilstein 2 IV 2078.]

Sebacic acid Preparation Products And Raw materials

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ECHEMI Editorial Reference

Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency.
Sebacic acid is a white granular powder. Melting point 153°F. Slightly soluble in water. Sublimes slowly at 750 mm Hg when heated to melting point.|DryPowder; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals|Solid|WHITE POWDER WITH CHARACTERISTIC ODOUR.
Sebacic acid is a white granular powder. Melting point 153°F. Slightly soluble in water. Sublimes slowly at 750 mm Hg when heated to melting point.|Sebacic acid is an alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. It has a role as a human metabolite and a plant metabolite. It is an alpha,omega-dicarboxylic acid and a lipid. It is a conjugate acid of a sebacate(2-) and a sebacate. It derives from a hydride of a decane.

Basic Info

Product Name:

Sebacic acid

Other Name:

Decanedioic acid;Sebacic acid;1,8-Octanedicarboxylic acid;1,10-Decanedioic acid;n-Decanedioic acid;NSC 19492;NSC 97405

CAS No.:

111-20-6

Molecular Formula:

C10H18O4

InChIKeys:

InChIKey=CXMXRPHRNRROMY-UHFFFAOYSA-N

Molecular Weight:

202.24800

Exact Mass:

202.25

EC Number:

203-845-5

UNII:

97AN39ICTC

ICSC Number:

1685

NSC Number:

19492

DSSTox ID:

DTXSID7026867

HScode:

2917131000

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

74.60000

XLogP3:

2.1

Appearance:

White powder

Density:

1.231 g/cm³

Melting Point:

130.8 °C

Boiling Point:

294.5 °C

Flash Point:

220 °C

Refractive Index:

1.422

Water Solubility:

Solubility in water, g/100ml: 0.1 (poor)

Storage Conditions:

Storage Room low temperature ventilation drying

Vapor Pressure:

1.24E-06mmHg at 25°C

Collision Cross Section:

141.9 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|152.7 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|144 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|146 Å² [M+Na-2H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|146.3 Å² [M-2H+Na]-

Air and Water Reactions:

Insoluble in water.

Reactive Group:

Acids, Carboxylic

Reactivity Profile:

SEBACIC ACID reacts exothermically to neutralize bases, both organic and inorganic. May react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Can react with active metals to form gaseous hydrogen and a metal salt. Such reactions are slow in the dry, but systems may absorb enough water from the air to allow corrosion of iron, steel, and aluminum parts and containers. Reacts slowly with cyanide salts to generate gaseous hydrogen cyanide. Reacts with solutions of cyanides to cause the release of gaseous hydrogen cyanide. May generate flammable and/or toxic gases and heat with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. May react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Can be oxidized exothermically by strong oxidizing agents and reduced by strong reducing agents. May initiate polymerization reactions.

Physical Dangers:

Dust explosion possible if in powder or granular form, mixed with air. If dry, it can be charged electrostatically by swirling, pneumatic transport, pouring, etc.

See More Sebacic acid Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

NO open flames. Prevent deposition of dust. Closed system, dust explosion-proof electrical equipment and lighting. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Separated from strong oxidants and strong bases.

See More Sebacic acid Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

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We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
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Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

19 Inquiries

Country	Product	Purchase Quantity	Date Posted
Germany	Sebacic Acid (CAS 111-20-6)	1 20' Fcl	Aug 28, 2026
Germany	Sebacic Acid	1 20' Fcl	Aug 25, 2026
Pakistan	Sebacic acid	100 KG	Jul 23, 2026
United States	Sebacic acid	1 MT	Jul 24, 2025
Italy	Sebacic Acid	20 MT	Jul 24, 2025
India	sebacic acid	5 TON	Apr 28, 2025
Poland	Sebacic acid	23 MT	Dec 10, 2024
India	sebacic acid	10 MT	Nov 27, 2024
South Africa	Sebacic Acid	5.00 KG	May 6, 2024
Netherlands	sebacic acid	1 MT	Dec 10, 2023
South Korea	Sebacic Acid	1 KG	Aug 26, 2026
India	Sebacic acid	25 MT	Aug 24, 2026
Poland	sebacic acid	46 MT	Jan 15, 2026
South Africa	sebacic acid	100000 MT	Oct 9, 2025
Saudi Arabia	Sebacic Acid	1.00 20' Fcl	May 17, 2024
Malaysia	sebacic acid	200 KG	Apr 8, 2026
United States	sebacic acid	200 MT	Jul 24, 2025
Pakistan	Sebacic Acid	10000.00 KG	Jan 24, 2025
India	SEBACIC ACID	1 TON	Jul 22, 2024

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Sebacic acid111-20-6C10H18O4

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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