Pyrrolo[1,2-b]pyridazine-6-carboxylic acid 97% Purity CAS 118768-13-1 Fused Heterocyclic Intermediate for Pharmaceutical Research

• • • • • Product Overview

          Pyrrolo[1,2-b]pyridazine-6-carboxylic acid is a fused heterocyclic compound containing a pyrrolo[1,2-b]pyridazine core with a carboxylic acid group at the 6-position. The pyrrolopyridazine scaffold is a privileged structure in medicinal chemistry, found in numerous bioactive molecules including kinase inhibitors and central nervous system therapeutics. This compound serves as a valuable synthetic intermediate for the preparation of pharmaceutical candidates and bioactive molecules.

          Chemical Properties

          • Molecular Formula: C₈H₆N₂O₂

          • Molecular Weight: 162.15 g/mol

          • Synonyms: Pyrrolo[1,2-b]pyridazine-6-carboxylic acid

          • Solubility: Soluble in DMSO, methanol, ethanol

          Synthetic Utility

          The carboxylic acid group at the 6-position enables various derivatization reactions, including amidation, esterification, and decarboxylative coupling. This compound is particularly useful in the synthesis of kinase inhibitors and other therapeutic agents.

          Quality Specifications

          • Purity: ≥97.0% (determined by HPLC area normalization)

          • Appearance: Off-white to pale yellow powder

          • Identification: Conforms to structure by NMR and Mass Spectrometry

          • Loss on Drying: ≤0.5%

          • Residue on Ignition: ≤0.1%

          • Heavy Metals: ≤10 ppm

          • Each batch is accompanied by a comprehensive Certificate of Analysis (COA).

          Packaging & Storage

          • Packaging: Available in 1g-1kg packaging. Custom packaging available upon request.

          • Storage: Store at 2-8°C, sealed, protected from light.

          • Shelf Life: 24 months when stored under recommended conditions.

Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

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We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

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