 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > 4-Chlorobenzoic acid for Sale > High Quality Organic Chemical Material Acemetacin Impurity 1acemetacin Ep Impurity a; Indometacin Ep Impurity a; 4-Chlorobenzoic

High Quality Organic Chemical Material Acemetacin Impurity 1acemetacin Ep Impurity a; Indometacin Ep Impurity a; 4-Chlorobenzoic buy - large image1

High Quality Organic Chemical Material Acemetacin Impurity 1acemetacin Ep Impurity a; Indometacin Ep Impurity a; 4-Chlorobenzoic buy - image1

High Quality Organic Chemical Material Acemetacin Impurity 1acemetacin Ep Impurity a; Indometacin Ep Impurity a; 4-Chlorobenzoic buy - image2

High Quality Organic Chemical Material Acemetacin Impurity 1acemetacin Ep Impurity a; Indometacin Ep Impurity a; 4-Chlorobenzoic buy - image3

High Quality Organic Chemical Material Acemetacin Impurity 1acemetacin Ep Impurity a; Indometacin Ep Impurity a; 4-Chlorobenzoic buy - image4

High Quality Organic Chemical Material Acemetacin Impurity 1acemetacin Ep Impurity a; Indometacin Ep Impurity a; 4-Chlorobenzoic

1 Inquiries

Unit Price:

$2450-2650/MT FOB

Get Latest Price 

CAS No.:

74-11-3

Grade:

Industrial Grade

Content:

99%

Port:

Qingdao

Brand:

Packaging:

25 kg pp drum

Sample Available:

Yes

Price valid (until):

2026-12-31

Contact Supplier

 Chat Now

Shandong Guozhao Import and Export Co., Ltd.

Company Type:

Distributor

Location:

China

Qualification:

Main Products:

CHEMICALS

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Property	Details
IUPAC Name	4-Chlorobenzoic acid
CAS No.	74-11-3
Molecular Formula	C7H5ClO2
Molecular Weight	156.57 g/mol
Appearance	White crystalline powder
Melting Point	238-241°C
Solubility	Water: 0.5 g/L (20°C);
pKa	3.98
UV λmax	235 nm, 280 nm
Applications	Pharmaceuticals, agrochemicals, polymers
Key Features	Thermal stability, high crystallinity
Storage Conditions	RT in dry environment
4-Chlorobenzoic acid is a versatile aromatic carboxylic acid widely used in pharmaceuticals, agrochemicals, and polymer synthesis. This para-substituted benzoic acid derivative features: Electron-withdrawing enhancing acidity (pKa 3.98) Regioselective reactivity for electrophilic substitutions Bifunctional handles for amidation/esterification Key applications include: ✓ Antibacterial drug intermediates (e.g., chloramphenicol) ✓ Liquid crystal precursors ✓ Corrosion inhibitors in cooling systems The group improves lipophilicity (logP 2.65) while the carboxyl enables salt formation or coupling reactions. High purity (>99%) ensures consistent performance in multistep syntheses.

We are a high-tech enterprise specializing in the R&D, production, and sales of fine chemicals and pharmaceutical intermediates. Located in Jinan-a city renowned for its rich history and vibrant innovation-the company leverages its strategic location and abundant industrial resources to provide high-quality chemical products and customized solutions to global clients.

As a leading player in the fine chemical industry, New Element Advanced Materials is driven by technological innovation. With an experienced R&D team and state-of-the-art laboratory facilities, we focus on developing efficient, environmentally friendly, and safe chemical products widely used in pharmaceuticals, agrochemicals, electronic materials, specialty chemicals, and other fields.

In the pharmaceutical intermediates sector, we strictly adhere to international quality management systems, ensuring high purity, stability, and compliance of our products to support global pharmaceutical manufacturers. Additionally, we emphasize green production and sustainable development, implementing clean production processes to minimize environmental impact.

Guided by the principle of "Customer First, Quality as Foundation," New Element Advanced Materials offers one-stop services-from product development and production to logistics and distribution. We firmly believe that continuous innovation and exceptional service are key to creating greater value for customers and fostering win-win partnerships.

Looking ahead, Suzhou New Element Advanced Materials Co., Ltd. will continue to deepen its expertise in fine chemicals and pharmaceutical intermediates, enhancing core competitiveness while collaborating with global clients to build a brighter future together.

Shop High Quality Organic Chemical Material Acemetacin Impurity 1acemetacin Ep Impurity a; Indometacin Ep Impurity a; 4-Chlorobenzoic-Detailed Image 1 1. Q: Are you manufacturer?
A: Yes, we are a factory with over 10 years of experience, and our products are popular in the market.

2. Q: What is your MOQ?
A: The minimum order quantity (MOQ) is 1 package.

3. Q: What packaging options do you provide?
A: We offer various packaging solutions, including:Iron drums,Plastic drums,IBC tanks,Flexitanks,ISO TANKS,Bags(Other packaging options can be discussed based on customer needs).

4. Q: What payment terms do you accept?
A: We mainly accept TT (Bank Transfer) and LC (Letter of Credit). Other payment methods can be negotiated.

5. Q: Can I request a sample?
A: Free samples are available, but shipping costs are to be covered by the buyer. For high-value products, a sample fee may apply.

6. Q: How long does sample delivery take?
A: Typically 7-10 days, depending on location and product availability.

7. Q: Why does the quoted price differ from the listed price?
A: Chemical prices are subject to market fluctuations, so quotes are adjusted accordingly.

8. Q: Do you offer discounts?
A: Yes, discounts are available based on order quantity.

9. Q: What is your delivery time?
A: We ensure fast and reliable shipping. Goods are usually dispatched within 3-5 days after payment confirmation.

10. Q: How do you ensure product quality?
A: Our dedicated R&D team ensures strict quality control. Each batch is tested, and a Certificate of Analysis (COA) is provided before shipment.

ECHEMI Editorial Reference

white to light yellow crystal powder
Triclinic crystals or light fluffy white powder. (NTP, 1992)|ODOURLESS WHITE SOLID IN VARIOUS FORMS.
Triclinic crystals or light fluffy white powder. (NTP, 1992)|4-chlorobenzoic acid is a monochlorobenzoic acid carrying a chloro substituent at position 4. It has a role as a bacterial xenobiotic metabolite. It derives from a benzoic acid. It is a conjugate acid of a 4-chlorobenzoate.
white to light yellow crystal powder. Soluble in methanol, anhydrous ethanol and ether, very slightly soluble in water, toluene and 95% ethanol.
Triclinic crystals or light fluffy white powder.4-Chlorobenzoic acid is a degradation product of indomethacin. It is degraded by Acinetobacter sp. strain ST-1 and causes its dehalogenation to yield 4-hydroxybenzoic acid under both aerobic and anaerobic conditions.

Basic Info

Product Name:

4-Chlorobenzoic acid

Other Name:

Indometacin EP Impurity A;Indomethacin EP Impurity A;Acemetacin Impurity 1（Acemetacin EP Impurity A）;Bezafibrate Impurity 2（Bezafibrate EP Impurity B）;Indomethacin USP RC B;AKOS 92635;AKOS BBS-00003713;RARECHEM AL BO 0054

CAS No.:

74-11-3

Molecular Formula:

C7H5ClO2

InChIKeys:

XRHGYUZYPHTUJZ-UHFFFAOYSA-N

Molecular Weight:

156.57

Exact Mass:

156.57

BRN:

907196

EC Number:

200-805-9

UNII:

IC7888DF4L

ICSC Number:

0503

NSC Number:

32738|8444

TSCA:

TSCA listed

DSSTox ID:

DTXSID9024772

Color/Form:

White to yellow

HScode:

29163900

Categories:

Bulk Drug Intermediates

Characteristics

λmax:

284nm(EtOH)(lit.)

PSA:

37.30000

XLogP3:

2.7

Appearance:

Triclinic crystals or light fluffy white powder. (NTP, 1992)

Density:

1.540

Melting Point:

238-241 °C(lit.)

Boiling Point:

274-276 °C

Flash Point:

127.5±19.8 °C

Refractive Index:

1.5812 (estimate)

Water Solubility:

soluble in hot water

Storage Conditions:

Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Vapor Pressure:

2.92X10-5 mm Hg at 25 deg C (est)

Vapor Density:

Relative vapour density (air = 1): 5.4

Toxicity:

LD50 orally in Rabbit: 1170 mg/kg

PH:

4.3 (0.08g/l, H2O, 20℃)

PKA:

3.98(at 25℃)

Henrys Law Constant:

2.5×101mol/(m3Pa) at 25℃, Abraham and Jr. (2019)

Dissociation Constants:

3.98 (at 25 °C)|pKa = 3.98|pKa = 4.03

Collision Cross Section:

127.6 Å² [M-H]-

Experimental Properties:

White, odorless, crystalline powder, freely soluble in water /p-Chlorobenzoic acid, sodium salt/|Nearly white, course powder. Soluble in methanol, alcohol, ether, and hot water /Chlorobenzoic acid/|Hydroxyl radical reaction rate constant = 1X10-12 cu cm/molec-sec at 25 °C (est)

Air and Water Reactions:

Insoluble in water.

Reactive Group:

Acids, Carboxylic

Reactivity Profile:

4-Chlorobenzoic acid is incompatible with strong oxidizing agents and strong bases.

Autoignition Temperature:

545 °C

Critical Temperature & Pressure:

room temp

See More 4-Chlorobenzoic acid Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

See More 4-Chlorobenzoic acid Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
CHEMICALS

Location:
No. 109, Chailu Street, Qingnian Park Subdistrict, Huaian District, Jinan City, Shandong Province 280

Year of Establishment:
2026

Shandong Guozhao Import and Export Co., Ltd., located at No. 280, Chalu Street, Qingnian Park Subdistrict, Huaiyin District, Jinan City, Shandong Province, primarily engages in import and export of goods; sales of chemical products (excluding licensed chemical products); sales of specialty chemical products (excluding hazardous chemicals); sales of plastic products; sales of metal products; sales of building materials; sales of architectural decoration materials; sales of daily-use chemical products; sales of food additives; sales of feed additives; sales of fertilizers; sales of batteries; and general cargo warehousing services (excluding items requiring licensing or approval, such as hazardous chemicals).

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Pakistan	chlorobenzoic acid	20 TON	Jul 15, 2024

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
4-Chlorobenzoic acid	industrial Grade/98		Hangzhou KieRay Chem Co.,LTD	Inquiry
4-Chlorobenzoic acid	/99.00		HANGZHOU LEAP CHEM CO., LTD.	Inquiry
Para Chlorobenzoic acid	Pharmaceutical Grade/99	$4.2/KG FOB	Chemcrux Enterprises Ltd.	Inquiry
4-Chlorobenzoic acid 99% high purity certified Professional producer Greenbo	Industrial Grade/99		Greenbo Biochem	Inquiry
China Most Professional Factory Supply High Qulity 4-Chlorobenzoic acid CAS 74-11-3	Pharmaceutical Grade/99		LEADER BIOCHEMICAL GROUP	Inquiry

High Quality Organic Chemical Material Acemetacin Impurity 1acemetacin Ep Impurity a; Indometacin Ep Impurity a; 4-Chlorobenzoic

Product Description

Seller Information