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Ritodrine

Ritodrine structure

CAS No:
26652-09-5
Formula:
C17H21NO3
Chemical Name:
Ritodrine
Synonyms:
Benzenemethanol,4-hydroxy-α-[(1R)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-,(αS)-rel-;Benzenemethanol,4-hydroxy-α-[1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-,(R*,S*)-;Benzyl alcohol,p-hydroxy-α-[1-[(p-hydroxyphenethyl)amino]ethyl]-,erythro-;rel-(αS)-4-Hydroxy-α-[(1R)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]benzenemethanol;Ritodrine;(±)-Ritodrine;Lavopa;52447-10-6
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

4-[2-[[1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]phenol is a secondary amino compound that is 4-(2-amino-1-hydroxypropyl)phenol in which one of the hydrogens attached to the nitrogen is replaced by a 2-(4-hydroxyphenyl)ethyl group. It is a member of benzyl alcohols, a polyphenol, a secondary alcohol and a secondary amino compound.|An adrenergic beta-2 agonist used to control PREMATURE LABOR.

Ritodrine Basic Attributes

Molecular Weight：

287.35

Exact Mass：

287.35

EC Number：

247-879-9

DSSTox ID：

DTXSID7048534

Characteristics

PSA：

72.72000

XLogP3：

2.74290

Density：

1.213g/cm3

Melting Point：

88-90 °C

Boiling Point：

512.3ºC at 760mmHg

Flash Point：

175.6ºC

Refractive Index：

1.618

Drug Information

MeSH：

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)|Compounds bind to and activate ADRENERGIC BETA-2 RECEPTORS. (See all compounds classified as Adrenergic beta-2 Receptor Agonists.)|Drugs that prevent preterm labor and immature birth by suppressing uterine contractions (TOCOLYSIS). Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete. (See all compounds classified as Tocolytic Agents.)

MeSH Entry Terms：

DU 21220

Ritodrine Use and Manufacturing

Relaxant (smooth muscle).

Computed Properties

Molecular Weight:287.35
XLogP3:2.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:287.15214353
Monoisotopic Mass:287.15214353
Topological Polar Surface Area:72.7
Heavy Atom Count:21
Complexity:284
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes