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Miocamycin

Miocamycin structure

CAS No:
55881-07-7
Formula:
C45H71NO17
Chemical Name:
Miocamycin
Synonyms:
Leucomycin V,3B,9-diacetate 3,4B-dipropanoate;Oxacyclohexadecane,leucomycin V deriv.;3′′,9-Diacetylmydecamycin;Mom;Miokamycin;Midecamycin acetate;9,3′′-Di-O-acetylmidecamycin;Miocamycin;Ponsinomycin;Acecamycin;95893-18-8;122413-78-9;77950-54-0;89591-92-4
Categories:
Active Pharmaceutical Ingredients > Antibiotics

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Miocamycin Basic Attributes

Molecular Weight：

898.046

Exact Mass：

898.04

EC Number：

259-879-6

Characteristics

PSA：

218.19000

XLogP3：

3.90900

Density：

1.2 g/cm3

Melting Point：

220 °C (decomp)

Boiling Point：

878.7ºC at 760 mmHg

Flash Point：

485.2ºC

Refractive Index：

1.524

Specific rotation：

D25 -53° (c = 1.0 in chloroform); D20 -74° (c = 1 in methanol)

Miocamycin Use and Manufacturing

It belongs to antibiotics and is used for infection caused by staphylococcus, hemolytic streptococcus, pneumococcus, influenza bacillus, etc.

Computed Properties

Molecular Weight:898.0
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:18
Rotatable Bond Count:18
Exact Mass:897.47219980
Monoisotopic Mass:897.47219980
Topological Polar Surface Area:218
Heavy Atom Count:63
Complexity:1590
Defined Atom Stereocenter Count:16
Undefined Bond Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

This product belongs to the macrolide antibiotics, and its antibacterial spectrum is similar to that of erythromycin, but its antibacterial effect is slightly weaker. It has good activity against Gram-positive bacteria and Neisseria. This product is not easy to induce bacterial resistance, and some erythromycin-resistant Staphylococcus aureus can still be sensitive to this product. This product works by acting on the 50S subunit of the bacterial ribosome, hindering the synthesis of bacterial proteins, and is a growth-stage antibacterial drug.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Acetyl Midecamycin Granules
Ingredients	Acetylmidecamycin.
Indication	This product can inhibit the normal metabolism of theophylline. When used in combination with theophylline, it can cause an abnormal increase in theophylline blood concentration and lead to poisoning or even death. Therefore, theophylline blood concentration should be monitored when the two drugs are used in combination.
Specifications	0.2g (200,000 units)
Manufacturer	CSPC OUYI Pharmaceutical Co., Ltd.

Acetyl midecamycin dry suspension
Ingredients	The main ingredient of this product is acetyl midecamycin.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	0.2 g (200,000 units)
Manufacturer	Shantou S.E.Z Meiji Pharmaceuticals Co., Ltd.

Acetyl Midecamycin Granules
Ingredients	The main ingredient of this product is acetyl midecamycin
Indication	This product can inhibit the normal metabolism of theophylline. When used in combination with theophylline, it can cause an abnormal increase in theophylline blood concentration and lead to poisoning or even death. Therefore, theophylline blood concentration should be monitored when the two drugs are used in combination.
Specifications	0.1g (100,000 units)
Manufacturer	CSPC OUYI Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

CSPC OUYI Pharmaceutical Co., Ltd.

China
Active
Shandong Anhong Pharmaceutical Co., Ltd.

China
Inactive