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2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide

2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide structure

CAS No:
1403764-72-6
Formula:
C16H17N3O4S
Chemical Name:
2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Synonyms:
Benzenesulfonamide,2-methoxy-N-(1,2,3,4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl)-;2-Methoxy-N-(1,2,3,4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl)benzenesulfonamide;2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide;PFI 1;PF 6405761;2-Methoxy-N-(3-methyl-2-oxo-1,4-dihydroquinazolin-6-yl)benzenesulfonamide;133687-07-7
Categories:
Biochemical Engineering > Inhibitors

Description

PFI-1 is a selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM in a cell-free assay.

Molecular Weight：

347.4

Exact Mass：

347.39

PSA：

96.1

XLogP3：

1.2

Appearance：

white to beige

Density：

1.4±0.1 g/cm3

Refractive Index：

1.628

Water Solubility：

DMSO: ≥10mg/mL

Storage Conditions：

2-8°C

Transport codes：

NONH for all modes of transport

wgk germany：

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