α-Hydroxytamoxifen
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α-Hydroxytamoxifen
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CAS No:
97151-02-5
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Formula:
C26H29NO2
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Chemical Name:
α-Hydroxytamoxifen
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Synonyms:
Benzeneethanol,β-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-α-methyl-,(βE)-;Benzeneethanol,β-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-α-methyl-,(E)-;(βE)-β-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]-α-methylbenzeneethanol;α-Hydroxytamoxifen
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CAS No:
Characteristics
32.7
5.9
1.094g/cm3
115-119°C
533.8ºC at 760 mmHg
276.6ºC
1.595
Amber Vial, -20°C Freezer
Drug Information
Alpha-Hydroxytamoxifen is a known human metabolite of tamoxifen.
alpha-hydroxytamoxifen
α-Hydroxytamoxifen Use and Manufacturing
A metabolite of the chemotherapeutic drug Tamoxifen (T006000). Exhibits a more potent estrogen agonist/antagonist activity than the parent drug.Also active as an intramembranous inhibitor of lipid peroxidation.
Computed Properties
Molecular Weight:387.5
XLogP3:5.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:387.219829168
Monoisotopic Mass:387.219829168
Topological Polar Surface Area:32.7
Heavy Atom Count:29
Complexity:495
Undefined Atom Stereocenter Count:1
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes