3-Methoxy-4-nitroaniline
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3-Methoxy-4-nitroaniline
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CAS No:
16292-88-9
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Formula:
C7H8N2O3
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Chemical Name:
3-Methoxy-4-nitroaniline
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Synonyms:
Benzenamine,3-methoxy-4-nitro-;m-Anisidine,4-nitro-;3-Methoxy-4-nitrobenzenamine;3-Methoxy-4-nitroaniline
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CAS No:
Characteristics
81.1
1.3
1.2089 (estimate)
158-160 °C
337.07°C (rough estimate)
175.9±22.3 °C
1.6010 (estimate)
3-Methoxy-4-nitroaniline Use and Manufacturing
General procedure: beta-Cyclodextrin (30 mol %), isatoic anhydride (1.0 mol eq.) and substituted isatin (1.0 mol eq.), were mixed in 8 mL water followed by stirring for 0.5 h at room temperature. Then primary amine (1.0 mol eq.) was added and reaction mixture was stirred vigorously upto disappearance of reactants on TLC (monitored by silica TLC). After completion reaction mixture was extracted by ethyl acetate and evaporated under reduced pressure. Solid residue was further crystallized by methanol and filtrate was kept for catalyst recovery.
Computed Properties
Molecular Weight:168.15
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:168.05349212
Monoisotopic Mass:168.05349212
Topological Polar Surface Area:81.1
Heavy Atom Count:12
Complexity:169
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes