7-BroMo-iMidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester
-
7-BroMo-iMidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester
structure -
-
CAS No:
1134327-98-2
-
Formula:
C10H9BrN2O2
-
Chemical Name:
7-BroMo-iMidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester
-
Synonyms:
Ethyl 7-bromoimidazo[1,2-a]pyridine-3-carboxylate;7-Bromo-imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester;Ethyl7-Bromoimidazo[1,2-a]pyridine-3-carboxylate;SCHEMBL2051512;CTK8C4546;DTXSID70736703;Imidazo[1,2-a]pyridine-3-carboxylic acid, 7-bromo-, ethyl ester;ANW-72322;MFCD09994702;MFCD11045695
-
CAS No:
7-BroMo-iMidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester Basic Attributes
269.09466
267.984741
DTXSID70736703
2933990090
7-BroMo-iMidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester Use and Manufacturing
To a solution of sulfuric acid (4.54 g, 46.24 mmol, 2.46 mL, 1.6 eq) and ethanol (75 mL) at 0 °C was added Example 102A (16.90 g, 89.59 mmol, 3.1 eq) and 2-amino-4- bromopyridine (5.00 g, 28.90 mmol, 1 eq). The reaction was stirred at 80 °C for 5 hr. The reaction was cooled to 25 °C and was diluted with water. The aqueous solution was adjusted to pH=7, and extracted with ethyl acetate (300 mL*3). The combined organic phase was washed with brine (200 mL*2), dried with anhydrous sodium sulfate, filtered and concentrated in vacuo. The residue was purified by silica gel chromatography. Example 102B (1.70 g, 6.32 mmol, yield =22percent) was obtained as a white solid. (0193) [0114] MR: (CDCb, 400MHz): ppm 9.19 (d, J=7.2 Hz, 1H), 8.27 (s, 1H), 7.93 (s, 1H), 7.16 (dd, J=1.6, 7.6 Hz, 1H), 4.43 (q, J=7.6 Hz, 2H), 1.43 (t, J=7.2 Hz, 3H).
Computed Properties
Molecular Weight:269.09
XLogP3:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:267.98474
Monoisotopic Mass:267.98474
Topological Polar Surface Area:43.6
Heavy Atom Count:15
Complexity:250
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 7-BroMo-iMidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester
-
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives
Learn More Other Chemicals
-
Cyclopropanecarboxylic acid, 1-formyl-2-methyl-, ethyl ester (9CI)
260261-27-6
-
3-CYCLOPROPYL-2-METHYL-3-OXO-PROPIONIC ACID ETHYL ESTER
21741-37-7
-
CYCLOPENTYL-CARBAMIC ACID PHENYL ESTER
58713-31-8
-
3-Cyclopentene-1-carboxylic acid, 1-(chlorocarbonyl)-, ethyl ester (9CI) Formula
76910-09-3
-
2'-Deoxy-N-trimethylsilyl-3'-O-trimethylsilylcytidine 5'-phosphoric acid bis(trimethylsilyl) ester Formula
32645-72-0
-
4,6-Dichloro-1H-indole-2,3-dicarboxylic acid diethyl ester Formula
146012-24-0
-
2-[(2,6-Dichlorophenyl)sulfonyl]acetic acid ethyl ester Structure
1154228-17-7
-
Dibenzoic acid 2-ethylhexamethylene ester Structure
25724-54-3
-
What is DIBOC-6-TRIMETHYLSTANNYL-L-PHENYLALANINE ETHYL ESTER
845882-24-8
-
What is 1,4-DIBENZYL-7-PHENYL-6-THIOXO-1,4,7-TRIAZA-SPIRO[4.4]NON-8-ENE-9-CARBOXYLIC ACID ETHYL ESTER
885722-38-3
7-BroMo-iMidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester
SDSRequest for Quotation