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Home > Encyclopedia > 2-Bromo-N,N-dimethylbenzenemethanamine

2-Bromo-N,N-dimethylbenzenemethanamine

2-Bromo-N,N-dimethylbenzenemethanamine structure

2-Bromo-N,N-dimethylbenzenemethanamine 

structure
  • CAS No:

    1976-04-1

  • Formula:

    C9H12BrN

  • Chemical Name:

    2-Bromo-N,N-dimethylbenzenemethanamine

  • Synonyms:

    Benzenemethanamine,2-bromo-N,N-dimethyl-;Benzylamine,o-bromo-N,N-dimethyl-;2-Bromo-N,N-dimethylbenzenemethanamine;2-Bromo-N,N-dimethylbenzylamine;o-Bromo-N,N-dimethylbenzylamine;2-((Dimethylamino)methyl)bromobenzene;1-Bromo-2-[(dimethylamino)methyl]benzene;NSC 54514;NSC 62161;2-Bromobenzyldimethylamine;[(2-Bromophenyl)methyl]dimethylamine;1-(2-Bromophenyl)-N,N-dimethylmethanamine

2-Bromo-N,N-dimethylbenzenemethanamine Basic Attributes

214.11

214.10

217-831-1

62161|54514

DTXSID00173440

Characteristics

3.2

2.75

1.3±0.1 g/cm3

124-126 °C

108-112 °C @ Press: 20 Torr

104.4±0.0 °C

1.552

0.0986mmHg at 25°C

Safety Information

8

1760

Xi

Irritant

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

2-Bromo-N,N-dimethylbenzenemethanamine Use and Manufacturing

Methods of Manufacturing

By the reaction of o-bromobenzyl bromide and dimethylamine. The o-bromobenzyl bromide and dimethylamine solution is heated to 80-90°C and the pressure is about 0.2MPa. Under these conditions, the reaction is 8-10h, the tail gas is absorbed by water, the reactants are cooled to a constant temperature, and the layers are allowed to stand. The lower oily substance is distilled under reduced pressure, and the 108-112°C (2.67kPa) fraction is collected to obtain 90% o-bromide Dimethylbenzylamine.

Uses

Pharmaceutical intermediates.

Computed Properties

Molecular Weight:214.10
XLogP3:2.4
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:213.01531
Monoisotopic Mass:213.01531
Topological Polar Surface Area:3.2
Heavy Atom Count:11
Complexity:114
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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