4-Bromo-N-methylbenzamide 98%

4-Bromo benzoyl chloride (5.0g, 22.8 mmol) was added to DCM (100 ml), to this was added TEA (7.0 ml, 50.2 mmol) followed by the slow addition of methylamine (20 ml, 2.0N in THF). The reaction was stirred for 1 hour before being quenched with HCl (2.0 N; 50 ml), EPO To stirred solution of 4-bromobenzoic acid (6.00 g, 29.8 mmol) in methylene chloride (80 mL) was added N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (6.30 g, 32.9 mmol), 4-(dimethylamino)pyridine (7.70 g, 63.0 mmol) and methylamine hydrochloride (2.23 g, 33.0 mmol). The mixture was stirred overnight and then washed with 1.0 N hydrochloric acid, dried (Na15-D-2 To a solution of 4-bromobenzoic acid (402.0mg, 2mmol) in DMF (10 mL), was added HATU(836.5mg, 2.2 mmol) and DIEA (697.0μL, 4mmol). After stirring for 5 minutes at room temperature, methylamine hydrochloride salt (135.0mg, 2mmol) was added. The solution was stirred at rt overnight. EPO

Molecular Weight:214.06
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:212.97893
Monoisotopic Mass:212.97893
Topological Polar Surface Area:29.1
Heavy Atom Count:11
Complexity:141
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes