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Butoxamine

Butoxamine structure

CAS No:
1937-89-9
Formula:
C15H25NO3
Chemical Name:
Butoxamine
Synonyms:
Benzenemethanol,α-[(1R)-1-[(1,1-dimethylethyl)amino]ethyl]-2,5-dimethoxy-,(αS)-rel-;Benzyl alcohol,α-[1-(tert-butylamino)ethyl]-2,5-dimethoxy-,DL-erythro-;Benzenemethanol,α-[1-[(1,1-dimethylethyl)amino]ethyl]-2,5-dimethoxy-,(R*,S*)-(±)-;rel-(αS)-α-[(1R)-1-[(1,1-Dimethylethyl)amino]ethyl]-2,5-dimethoxybenzenemethanol;(±)-Butoxamine;Butaxamine;Butoxamine;Benzenemethanol,α-[1-[(1,1-dimethylethyl)amino]ethyl]-2,5-dimethoxy-,(R*,S*)-;7518-13-0;13098-17-4
Categories:
Organic Chemistry > Amides

Description

A beta-2 selective adrenergic antagonist. It is used primarily in animal and tissue experiments to characterize BETA-2 ANDRENERGIC RECEPTORS.

Butoxamine Basic Attributes

Molecular Weight：

267.36

Exact Mass：

267.36

DSSTox ID：

DTXSID30172986

Characteristics

PSA：

50.7

Boiling Point：

127-128 °C @ Press: 0.3 Torr

Drug Information

MeSH：

Drugs that bind to and block the activation of ADRENERGIC BETA-2 RECEPTORS. (See all compounds classified as Adrenergic beta-2 Receptor Antagonists.)|Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here. (See all compounds classified as Sympatholytics.)|Substances which lower blood glucose levels. (See all compounds classified as Hypoglycemic Agents.)|Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS. (See all compounds classified as Hypolipidemic Agents.)

MeSH Entry Terms：

Butaxamine

Computed Properties

Molecular Weight:267.36
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:267.18344366
Monoisotopic Mass:267.18344366
Topological Polar Surface Area:50.7
Heavy Atom Count:19
Complexity:265
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes