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Caroxazone

Caroxazone structure

Caroxazone 

structure
  • CAS No:

    18464-39-6

  • Formula:

    C10H10N2O3

  • Chemical Name:

    Caroxazone

  • Synonyms:

    2H-1,3-Benzoxazine-3(4H)-acetamide,2-oxo-;2-Oxo-2H-1,3-benzoxazine-3(4H)-acetamide;Caroxazone;FI 6654;4H-3-(Carbamoylmethyl)-1,3-benzoxazin-2-one;Timostenil;2-(2-Oxo-4H-1,3-benzoxazin-3-yl)acetamide;2-(2-Oxo-3,4-dihydro-2H-1,3-benzoxazin-3-yl)acetamide

Description

Caroxazone is a benzoxazine.|Caroxazone is an antidepressant that has been withdrawn from the market. It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. However, it presents a five-fold preference for the MAO-B subtype.

Caroxazone Basic Attributes

206.201

206.20

242-345-1

807N226MNL

DTXSID10171598

2934999090

Characteristics

72.6

1.12450

1.345g/cm3

204 °C

435.1ºC at 760mmHg

216.9ºC

1.594

Safety Information

III

6.1(b)

3249

Drug Information

For the treatment of depression.

2,3-dihydro-4H-1,3-benzoxazin-2-one-3-acetamide

Caroxazone Use and Manufacturing

Caroxazone acts as an irreversible, nonselective MAO inhibitor, displaying antidepressant characteristics.

Computed Properties

Molecular Weight:206.20
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:206.06914219
Monoisotopic Mass:206.06914219
Topological Polar Surface Area:72.6
Heavy Atom Count:15
Complexity:280
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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