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Home > Encyclopedia > Clentiazem maleate

Clentiazem maleate

pharmaceutical raw materials
Clentiazem maleate structure

Clentiazem maleate 

structure
  • CAS No:

    96128-92-6

  • Formula:

    C22H25ClN2O4S.C4H4O4

  • Chemical Name:

    Clentiazem maleate

  • Synonyms:

    1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-8-chloro-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,(2S,3S)-,(2Z)-2-butenedioate (1:1);1,5-Benzothiazepin-4(5H)-one,3-(acetyloxy)-8-chloro-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-,(2S-cis)-,(Z)-2-butenedioate (1:1);TA 3090;Clentiazem maleate;(S,S)-Clentiazem maleate;Logna

Clentiazem maleate Basic Attributes

565.03506

564.133

YN4F0N5QE0

Characteristics

159

160.5-161.5 °C

D20 +76.5° (c = 1 in methanol)

Drug Information

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)|A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)|Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. (See all compounds classified as Platelet Aggregation Inhibitors.)

3-acetoxy-8-chloro-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4-(5H)-one maleate

Computed Properties

Molecular Weight:565.0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:9
Exact Mass:564.1333148
Monoisotopic Mass:564.1333148
Topological Polar Surface Area:159
Heavy Atom Count:38
Complexity:719
Defined Atom Stereocenter Count:2
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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