COCHLIOQUINONE A
-
COCHLIOQUINONE A
structure -
-
CAS No:
32450-25-2
-
Formula:
C30H44O8
-
Chemical Name:
COCHLIOQUINONE A
-
Synonyms:
COCHLIOQUINONE A;(3R)-9-[(1S,2R,3S)-2-Acetyloxy-1,3-dimethylpentyl]-1,2,3,4aβ,5,6,6a,12,12aβ,12b-decahydro-12β-hydroxy-3α-(1-hydroxy-1-methylethyl)-6aα,12bα-dimethylpyrano[3,2-a]xanthene-8,11-dione;Luteoleersin
-
CAS No:
COCHLIOQUINONE A Use and Manufacturing
Cochlioquinone A, a bioactive compound isolated from D. sacchari and Bipolaris sp., is an inhibitor of diacylglycerol kinase (DGK; Ki = 3.1 μM) and diacylglycerol acyltransferase (DGAT; IC50 = 5.6 μM). It has been shown to reduce the concentration of phosphatidic acid in T cell lymphoma with an IC50 value of 3 μM. It is also reported to compete with macrophage inflammatory protein-1α for binding to human CCR5 chemokine receptors with an IC50 value of 11 μM.[Cayman Chemical]
Computed Properties
Molecular Weight:532.7
XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:7
Exact Mass:532.30361836
Monoisotopic Mass:532.30361836
Topological Polar Surface Area:119
Heavy Atom Count:38
Complexity:1070
Defined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Learn More Other Chemicals
-
dehydrotanshinone II A
119963-50-7
-
Megalomicin A bis(potassium dihydrogen phosphate)
23319-48-4
-
Dechloropenitrem A
78213-66-8
-
Dexylosylbenanomicin A Formula
133806-62-9
-
Glucofrangulin A Formula
21133-53-9
-
2'-Demethylbenanomicin A Formula
133806-63-0
-
diazaquinomycin A Structure
87614-40-2
-
Pyropheophorbide a Structure
24533-72-0
-
What is Ditrisarubicin A
87399-21-1
-
What is methylenecyclopropyl acetyl-coenzyme A
56898-43-2