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desmethylazelastine

desmethylazelastine structure

desmethylazelastine 

structure
  • CAS No:

    47491-38-3

  • Formula:

    C21H22ClN3O

  • Chemical Name:

    desmethylazelastine

  • Synonyms:

    desmethylazelastine;4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1H-azepin-4-yl)-1(2H)-phthalazinone;Demethylazelastine;N-Desmethyl Azelastine;4-(p-Chlorobenzyl)-2-[(hexahydro-1H-azepin)-4-yl]phthalazin-1(2H)-one;Azelastine Hydrochloride Impurity;AzelastinIMP

Description

Pale Yellow Solid

desmethylazelastine Basic Attributes

367.877

367.145

Characteristics

44.7

3.9

1.29g/cm3

544.1ºC at 760mmHg

282.8ºC

1.66

Refrigerator

Drug Information

4-(4-chlorobenzyl)-2-(perhydroazepinyl-(4))-1(2H)-phthala zinone

desmethylazelastine Use and Manufacturing

The main phase I metabolites of Azelastine

Computed Properties

Molecular Weight:367.9
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:367.1451400
Monoisotopic Mass:367.1451400
Topological Polar Surface Area:44.7
Heavy Atom Count:26
Complexity:529
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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