DANSYLAMINO-PITC
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DANSYLAMINO-PITC
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CAS No:
102417-94-7
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Formula:
C19H17N3O2S2
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Chemical Name:
DANSYLAMINO-PITC
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Synonyms:
DANSYLAMINO-PITC;DNSAPITC;4-[[5-(DIMETHYLAMINO)-1-NAPHTHYLSULFONYL]AMINO]PHENYLISOTHIOCYANATE;4-(DANSYLAMINO)PHENYL ISOTHIOCYANATE;4-(N-1-DIMETHYLAMINONAPHTHALENE-5-SULFONYLAMINO)PHENYL ISOTHIOCYANATE;4-(5-DIMETHYLAMINONAPHTH.-1-SULF.AMINO)&;DANSYLAMINO-PITC [FLUORESCENT COUPLING REAGENT FOR EDMAN DEGRADATION];fluorescentcouplingreagentforedmandegradation]
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CAS No:
Safety Information
3
42
22-24/25
Xn
Light Sensitive; Store at -20°C and Desicate.
|Danger|H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P272, P280, P285, P302+P352, P304+P341, P321, P333+P313, P342+P311, P363, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
DANSYLAMINO-PITC Use and Manufacturing
A fluorescent PITC homologue Edman-type reagent with similar coupling efficiency andrepetitive degradation yield to those of PITC.Naphthalene derivatives may be particularly useful for preparing fluorescent drug or ligand analogues that are expected to bind to hydrophobic sites in proteins or membranes.The lipophilicity of these reagents may also facilitate the labelling of sites within the membrane-spanning portions of cellular proteins.Fluorescence: max. Abs. l = 335nm, max. Em.l = 536nm (in methanol)
Computed Properties
Molecular Weight:383.5
XLogP3:5.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:383.07621914
Monoisotopic Mass:383.07621914
Topological Polar Surface Area:102
Heavy Atom Count:26
Complexity:617
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes