DEOXYMANNOJIRIMYCIN
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DEOXYMANNOJIRIMYCIN
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CAS No:
84444-90-6
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Formula:
C6H13NO4
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Chemical Name:
DEOXYMANNOJIRIMYCIN
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Synonyms:
DEOXYMANNOJIRIMYCIN;DMJ;3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2R,3R,4R,5R)-;1,5-Dideoxy-1,5-epimino-D-mannitol;1,5-Dideoxy-1,5-imino-D-mannitol;1-Deoxymannojirimycin;Antibiotic LU-1;LU-1
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CAS No:
Description
selectively inhibits a-D-mannosidases 1A/B and processing of N-linked glycoproteins, competitive, active site-directed inhibitor of mammalian Golgi a-D-mannosidase I
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Drug Information
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)|Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)
1 Deoxymannojirimycin
DEOXYMANNOJIRIMYCIN Use and Manufacturing
competitive inhibitor of glucosidase I and II; pig kidney trehalase inhibitor
Computed Properties
Molecular Weight:163.17
XLogP3:-2.3
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:163.08445790
Monoisotopic Mass:163.08445790
Topological Polar Surface Area:93
Heavy Atom Count:11
Complexity:132
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes