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Home > Encyclopedia > 2'-DEOXY-3,4,5,6-TETRAHYDROURIDINE

2'-DEOXY-3,4,5,6-TETRAHYDROURIDINE

2'-DEOXY-3,4,5,6-TETRAHYDROURIDINE structure

2'-DEOXY-3,4,5,6-TETRAHYDROURIDINE 

structure
  • CAS No:

    31962-88-6

  • Formula:

    C9H16N2O5

  • Chemical Name:

    2'-DEOXY-3,4,5,6-TETRAHYDROURIDINE

  • Synonyms:

    2'-DEOXY-3,4,5,6-TETRAHYDROURIDINE;1-(2-Deoxy-b-D-Erithro-Pentofuranosyl) Tetrahydro-4-Hydroxy-2(1H)- Pyrimidinone;2Deoxy-3,4,5,6-tetrahydrouridineDiscontinued;2Deoxytetrahydrouridine;Tetrahydrodeoxyuridine;1-(2-Deoxy--D-Erithro-Pentofuranosyl) Tetrahydro-4-Hydroxy-2(1H)- Pyrimidinone;(4S)-3,4,5,6-Tetrahydro-4β-hydroxy-1-(2-deoxy-β-D-ribofuranosyl)pyrimidin-2(1H)-one;RSRNLJYSWSSQMW-WMEPKMGJSA-N

  • Categories:

    Biochemical Engineering  >  Saccharides

2'-DEOXY-3,4,5,6-TETRAHYDROURIDINE Basic Attributes

232.234

232.10600

Characteristics

105.75000

-1.4

1.488g/cm3

617.8ºC at 760mmHg

327.4ºC

1.594

Drug Information

2'-deoxytetrahydrouridine

2'-DEOXY-3,4,5,6-TETRAHYDROURIDINE Use and Manufacturing

The novel compounds are specifically used to inhibit deaminating enzymes, which would inactivate cytosine arabinoside by conversion to uridine arabinoside. Cytosine arabinoside is used for its anti-viral, particularly anti-herpes and anticytotoxic activity in mammals and birds, as well as to destroy phages which interfere with the production of antibiotics.

Computed Properties

Molecular Weight:232.23
XLogP3:-1.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:232.10592162
Monoisotopic Mass:232.10592162
Topological Polar Surface Area:102
Heavy Atom Count:16
Complexity:275
Defined Atom Stereocenter Count:3
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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