DIMETHYL-(6-METHYL-2-P-TOLYL-IMIDAZO[1,2-A]PYRIDIN-3-YLMETHYL)-AMINE

Preparation of 6-methyI-2-(4-methylphenyI)imidazo[l, 2-a]pyridine-3- N, N-dimethylmethyl amine (8)Dissolved the 6-methyl-2-(4-methylphenyl)imidazo[l, 2-a]pyridine (200 grams, 0.92 mmol) in acetic acid (985 mL) under stirring. Cooled the above reaction mass to 0 - 5 23.45 liters of glacial acetic acid was taken into a reactor and 13.4 kg of 6-methyl-2-(4-methyl-phenyl)-imidazo [1, 2-α] pyridine was added to it.

3-(Dimethylaminomethyl)-6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridineis an impurity of Zolpidem (Z650000), a selective non-benzodiazepine GABAA receptor agonist.

Molecular Weight:279.4
XLogP3:2.9
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:279.173547683
Monoisotopic Mass:279.173547683
Topological Polar Surface Area:20.5
Heavy Atom Count:21
Complexity:335
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes