 Home > Encyclopedia > (E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT

(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT

(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT structure

CAS No:
115104-28-4
Formula:
C26H27ClN2O3S2
Chemical Name:
(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT
Synonyms:
CS-2183;(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT;L 660711, SODIUM SALT;3-[[[3-[(E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic acid;3-[[[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic acid;MK-571;MK-571 NA;MK-571 SODIUM SALT

Request for Quotation

Description

Yellow Solid

MK 571 is a member of quinolines.

MK-571 is a selective, orally active CysLT1receptor antagonist. It blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Kivalues of 0.22 nM and 2.1 nM, respectively, which is indicative of CysLT1receptor-mediated activity in these preparations. MK-571 effectively blocks LTD4activation of recombinant human and murine CysLT1receptors but is ineffective at blocking LTC4or LTD4activation of the recombinant human or murine CysLT2receptors.

(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT Basic Attributes

Molecular Weight：

515.09

Exact Mass：

515.09

DSSTox ID：

DTXSID5048390

Color/Form：

Yellow

Characteristics

PSA：

121.10000

XLogP3：

5.93

Density：

1.327±0.06 g/cm3(Predicted)

Melting Point：

65-70°C

Boiling Point：

712.3±60.0 °C(Predicted)

Flash Point：

384.6±32.9 °C

Refractive Index：

1.687

Storage Conditions：

Store at -20°C

PKA：

4.27±0.10(Predicted)

Critical Temperature & Pressure：

Store at -20°C

Safety Information

wgk germany：

WGK 1

Storage features：

Store at -20°C

Drug Information

MeSH：

A class of drugs designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level. (See all compounds classified as Leukotriene Antagonists.)|Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)

MeSH Entry Terms：

(3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)((3-dimethylamino-3-oxopropyl)thio)methyl)thiopropanoic acid

(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT Use and Manufacturing

A receptor antagonist for the treatment of respiratory diseases. Cysteinyl leukotriene receptor antagonist MK-571 alters bronchoalveolar lavage fluid proteome in asthma

Computed Properties

Molecular Weight:515.1
XLogP3:5.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:514.1151628
Monoisotopic Mass:514.1151628
Topological Polar Surface Area:121
Heavy Atom Count:34
Complexity:693
Undefined Atom Stereocenter Count:1
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Learn More Other Chemicals

Sulfuric acid, monodecyl ester, magnesium salt (2:1)

25446-93-9
Desacetyl Cephapirin SodiuM Salt

104557-24-6
D-Fructose, 1,6-bis(dihydrogen phosphate), sodium salt (1:4)

23784-19-2
Arsonic acid, methyl-, bismuth(3+) salt (3:2) Formula

85237-42-9
Poly(oxy-1,2-ethanediyl), α-(carboxymethyl)-ω-(decyloxy)-, sodium salt (1:1) Formula

38815-93-9
Benzenesulfonic acid, 2,2′-(1,2-ethenediyl)bis[5-[[4-amino-6-(phenylamino)-1,3,5-triazin-2-yl]amino]-, diammonium salt Formula

32866-17-4
Quino[2,3-b]acridine-2,9-disulfonic acid, 5,7,12,14-tetrahydro-7,14-dioxo-, aluminum salt (3:2) Structure

19795-24-5
Butanedioic acid, 2-sulfo-, 1-eicosyl ester, ammonium salt (1:2) Structure

94236-98-3
What is Phosphoric acid, monododecyl ester, ammonium salt (1:2)

65138-75-2
What is Phosphonic acid, [[(2-hydroxyethyl)imino]bis(methylene)]bis-, diammonium salt

84696-97-9

Hot Searches: reta price; ammonium sulfide; calcium sulfate compound; methanol price per gallon; barium sulfate suspension; raw cosmetic ingredients

Guide of (E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Learn More Other Chemicals

(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.