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(±)-Menthol

(±)-Menthol structure

CAS No:
89-78-1
Formula:
C10H20O
Chemical Name:
(±)-Menthol
Synonyms:
Cyclohexanol,5-methyl-2-(1-methylethyl)-,(1R,2S,5R)-rel-;Menthol,cis-1,3,trans-1,4-;Cyclohexanol,5-methyl-2-(1-methylethyl)-,(1α,2β,5α)-;Menthol,dl-;rel-(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexanol;Hexahydrothymol;Menthacamphor;Menthomenthol;Peppermint camphor;Menthol;Racemic menthol;dl-Menthol;(±)-Menthol;Racementhol;rac-Menthol;(1R,2S,5R)-rel-5-Methyl-2-(1-methylethyl)cyclohexanol;Fisherman's Friend Lozenges;Therapeutic Mineral Ice;NSC 2603;Thymomenthol;DL-Menthol;Meggezone;MENTHOL JP COS SP;15356-70-4
Categories:
Cosmetic Ingredient > Refreshing

Description

(±)-Menthol, also known as racemic menthol, is an organic compound with a unique chemical structure. Its chemical formula is C10H20O, indicating it is composed of ten carbon atoms, twenty hydrogen atoms, and one oxygen atom. This compound exists in the form of a white crystalline solid and has a very strong minty aroma, providing a cooling and refreshing sensation. (±)-Menthol is solid at room temperature and has a certain melting point, typically stable under ambient conditions. It is highly soluble, especially in alcohols and ethers, allowing it to easily dissolve in these solvents and exert its unique fragrance and cooling effect in various applications. Due to its distinct minty aroma and cooling sensation, (±)-Menthol is widely used in a variety of products, such as mint candies, chewing gum, toothpaste, mouthwash, and other personal care products. Additionally, it exhibits certain antibacterial and analgesic properties, making it applicable in some pharmaceutical formulations. With its wide range of uses and unique properties, (±)-Menthol has become a very important compound in the chemical and fragrance industries.

(±)-Menthol Basic Attributes

Molecular Weight：

156.26500

Exact Mass：

156.27

HScode：

2906110000

Characteristics

PSA：

20.23000

XLogP3：

2.43950

Appearance：

White crystalline solid with a peppermint odor and taste.

Density：

0.890 g/cm³

Melting Point：

41-43 °C

Boiling Point：

212 °C

Flash Point：

92ºC

Refractive Index：

1.4615

Water Solubility：

H2O: insoluble

Storage Conditions：

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition so

Vapor Pressure：

0.8 mm Hg ( 20 °C)

Toxicity：

LD50 orally in rats: 3180 mg/kg (Jenner)

Safety Information

Transport codes：

UN 1888 6.1/PG 3

wgk germany：

hazard class code：

R36/37/38

safety instructions：

S24/25

RTECS Number：

OT0350000

Marks：

Precautionary statement(s)：

P261-P280-P305 + P351 + P338

Hazard Statements：

H315-H318-H335

(±)-Menthol Use and Manufacturing

Flavoring agent in toothpastes & mouthwashes, in pharmaceuticals, principally flavoring agent in cigarettes, flavoring agent in aerosol room fresheners, in cosmetics, misc applications, topical antipruritic.

Computed Properties

Molecular Weight:156.26
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:156.151415257
Monoisotopic Mass:156.151415257
Topological Polar Surface Area:20.2
Heavy Atom Count:11
Complexity:120
Undefined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Ethanol

Acetic acid

Isopropanol

Hydrochloric acid

Sulfuric acid

Downstream Products

tert-Butyl acetate

Methylcyclopentane

Drug Function and Efficacy

Promote local circulation and have mild anti-inflammatory, analgesic and antipruritic effects

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Compound dexamethasone acetate cream
Ingredients	This product is a compound preparation, containing 0.75 mg of dexamethasone acetate, 10 mg of camphor, and 10 mg of menthol per gram. Excipients are: stearic acid, white vaseline, octadecyl alcohol, glycerin, sodium lauryl sulfate, ethyl hydroxybenzoate, dimethyl sulfoxide, and purified water.
Indication	If you are using other medicines, please consult your physician or pharmacist before using this product.
Specifications	20 g: 15 mg; 10 g: 7.5 mg

Chuanbei Loquat Syrup
Ingredients	Fritillaria cirrhosa fluid extract, Platycodon grandiflorum, loquat leaf, menthol. Auxiliary ingredients are sucrose and almond essence.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	10ml per tube, 100ml per bottle
Manufacturer	Jiangxi Heying Pharmaceutical Co., Ltd.

Cough Syrup
Ingredients	Loquat leaves, Platycodon grandiflorum, Fritillaria cirrhosa, Adenophora scabra, Polygala tenuifolia, Green tea, Menthol
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	100ml per bottle
Manufacturer	Ningbo Liwah Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

SYMRISE INC

United States
Active
Anhui Yinfeng Pharmaceutical Co., Ltd.

China
Active
Anhui Huaxin Biotech Co., Ltd.

China
Active

See More Registered Holders

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Guide of (±)-Menthol

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Material
Downstream Products
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Learn More Other Chemicals

(±)-Menthol

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