Diosgenin
-
Diosgenin
structure -
-
CAS No:
512-04-9
-
Formula:
C27H42O3
-
Chemical Name:
Diosgenin
-
Synonyms:
Spirost-5-en-3-ol,(3β,25R)-;Spirost-5-en-3β-ol,(25R)-;25D-Spirost-5-en-3β-ol;Spiro[8H-naphth[2′,1′:4,5]indeno[2,1-b]furan-8,2′-[2H]pyran],spirost-5-en-3-ol deriv.;(3β,25R)-Spirost-5-en-3-ol;Diosgenin;Nitogenin;(25R)-Spirost-5-en-3β-ol;25α-Spirost-5-en-3β-ol;NSC 33396
- Categories:
-
CAS No:
Description
Diosgenin, a steroidal saponin, can inhibit STAT3 signaling pathway.
Diosgenin is a sapogenin that is spirostan which is substituted by a hydroxy group at the 3beta position, contains a double bond at the 5-6 position, and has R- configuration at position 25. A natural product found in Dioscorea (wild yam) species, it is used as the starting point for the commercial synthesis of a number of steroids, including cortisone, pregnenolone and progesterone. It has a role as an apoptosis inducer, an antiviral agent, an antineoplastic agent and a metabolite. It is a 3beta-sterol, a spiroketal, a hexacyclic triterpenoid and a sapogenin. It derives from a hydride of a spirostan.|A spirostan found in DIOSCOREA and other plants. The 25S isomer is called yamogenin. Solasodine is a natural derivative formed by replacing the spiro-ring with a nitrogen, which can rearrange to SOLANINE.
Characteristics
38.69000
5.71390
Flaky or needle crystal
1.13 g/cm3
205.5 °C
527.1ºC at 760 mmHg
272.6ºC
1.564
chloroform: 20 mg/mL, clear, slightly yellow
Refrigerator
208.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Safety Information
NONH for all modes of transport
2
R36/37/38
S26; S36/37
WH1450000
Xi
Stable at normal temperatures and pressures.
Diosgenin Use and Manufacturing
Can be converted to pregnenolone and progesterone.
Lipids -> Sterol Lipids [ST] -> Sterols [ST01] -> Spirostanols and derivatives [ST0108]
Computed Properties
Molecular Weight:414.6
XLogP3:5.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Exact Mass:414.31339520
Monoisotopic Mass:414.31339520
Topological Polar Surface Area:38.7
Heavy Atom Count:30
Complexity:746
Defined Atom Stereocenter Count:11
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Skin conditioning, anti-inflammatory, anti-sensitivity, antibacterial
Recommended Suppliers of Diosgenin
-
![China]()
CN
2 YRS
Business licensedTrader Supplier of api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals,CATALYST AND AUXILIARY,FLAVORS AND FRAGRANCES,Chemical Pesticides,ADDITIVE -
![China]()
CN
1 YR
Business licensed Certified factoryManufactory Supplier of Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive,Herb extract,Antibiotics,API,Virginiamycin,Copper Peptide,Potassium iodide,Minoxidil,Praziquantel,Fipronil,Topiramate,Bromhexine,Furazolidone,Nitrofurazone,Clotrimazole,Mebendazole,Fenbendazole,Amprolium,Enramycin,SulfamethoxazoleInquiryCAS No.: 512-04-9Grade: Pharmaceutical GradeContent: 99% -
![China]()
CN
2 YRS
Business licensed Certified factoryManufactory Supplier of plant extrct -
![South Africa]()
ZA
3 YRS
Business licensedDistributor Supplier of Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid,Sodium Hydrosulfide,Acetic Acid Glacial,Trichloroisocyanuric Acid 90%,Hydrogen Peroxide,Calcium Carbide,Phosphoric Acid,Linear Alkylbenzene Sulfonic Acid,Sulphuric Acid,Ethanol 96%,Sodium BicarbonateInquiryCAS No.: 512-04-9Grade: Industrial GradeContent: 99% -
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of Herb Extracts,Cosmetic raw materails,APIInquiryCAS No.: 512-04-9Content: 0.00%
Learn More Other Chemicals
-
25-Deoxyecdysone
22005-50-1
-
compoundk
160729-91-9
-
7-[4-[4-(2-bromophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
203395-84-0
-
Moscatilin Formula
108853-14-1
-
beta-sitosterol sulfate Formula
24815-93-8
-
Cocoa butter Formula
8002-31-1
-
(2β,3β,5β,22S)-22,25-Epoxy-2,3,14,20-tetrahydroxycholest-7-en-6-one Structure
26361-67-1
-
escin IIa Structure
158732-55-9
-
What is Carvacryl acetate
6380-28-5
-
What is 13,28-Epoxy-16β-hydroxyolean-11-en-3β-yl 6-deoxy-3-O-(β-D-glucopyranosyl)-β-D-galactopyranoside
64340-44-9