1,1-Dichloro-1-fluoroethane

116.95000

116.95

605-613-2

O1A3ASY5PW

1712

9274

DTXSID2020422

Colorless liquid

2903730000

0

2.10720

1,1-dichloro-1-fluoroethane is a colorless liquid at ambient conditions.

1.250 g/cm³ @ Temp: 10 °C

-103.5 °C

32 °C

111.9ºC

1.3498 (50ºC)

Solubility in water, g/100ml at 20°C: 0.4

Store in a cool, dry location, away from incompatible materials. Avoid aluminum containers.

0.00829mmHg at 25°C

Relative vapour density (air = 1): 4.0

Explosive limits , vol% in air: 5.6-17.7

Weak ethereal odor

5.90e-15 cm3/molecule*sec

Ozone depletion potential: 0.08. (Ozone depletion potential relative to R11= 1.0. Scientific assessment of ozone: 1989.) /From table/|Heat capacity: 1.1556 kJ/kg-K at 25 °C (liquid); 0.7913 kJ/kg-K @ 25 °C(vapor at 1 atm)|Ozone depletion potential (ODP) 0.11; Global warming potential (GWP) 0.14 (ODP refers to R-11; GWP refers to CO2)

No rapid reaction with air. No rapid reaction with water.

Halogenated Organic Compounds

1,1-DICHLORO-1-FLUOROETHANE may be incompatible with strong oxidizing and reducing agents. May be incompatible with some amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. An explosion occurred when an emptied drum of this compound was cut into by a grinder; may be more flammable than once thought.

530-550 °C

The vapour is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen.

223.15 kJ/kg

Critical temperature: 210.3 °C; Critical pressure: 4.640 MPa

UN 9274

R59

S23; S36/37/39; S61; S59

KI0997000

Xi; N

Separated from strong acids. Cool. Keep in a well-ventilated room. Store in an area without drain or sewer access.

Stable.

P273, P501, P502

H412

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Dangerous ... on contact with acid or acid fumes, they emit highly toxic fumes. /Fluorides/|DANGEROUS ... ON CONTACT WITH ACIDS OR ACID FUMES THEY EVOLVE HIGHLY TOXIC CHLORIDE FUMES. /CHLORIDES/

Zakhari S, Aviado DM; Cardiovascular Toxicology of Aerosol Propellants, Refrigerants and Related Solvents; Target Organ Toxicology Series: Cardiovascular Toxicology, XII+ 388 pages; Raven Press: New York, NY 281-326 (1982). Review of the toxicology of aerosol propellants, refrigerants and related solvents on the cardiovascular system of humans.|Dekant W; Toxicology of Chlorofluorocarbon Replacements; Environmental Health Perspectives 104 (Supplement 1): 75-83 (1996). The toxicological properties of chlorofluorocarbon (CFC) replacements, created to have much lower ozone depleting potential than previously used chlorofluorocarbons, were reviewed.|Longstretch J; Inst Global Risk Res LLC 9119 Kirkdale Rd, Suite 200, Bethesda, MD 20817, USA; Journal of Photochemistry and Photobiology B Biology 46 (1-3): 20-39 (1998). The health risks associated with ozone depletion will principally be those due to increased ultraviolet B (UV-B) radiation in the environment, i.e., increased damage to the eyes, the immune system, and the skin.|Mcculloch A; Sources of hydrochlorofluorocarbons, hydrofluorocarbons and fluorocarbons and their potential emissions during the next twenty five years; Environmental Monitoring and assessment 31 (1-2): 167-174 (1994). In common with CFCs, the classes of compounds in the title wholly anthropogenic sources. CFCs are used for refrigeration, air-conditioning, foam blowing, solvent cleaning and propelling aerosols and, in each case equipment has been designed to make the most efficient use of the properties of individual compounds.

Gives off irritating or toxic fumes (or gases) in a fire.

|Warning|H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]|P273, P501, and P502|H412 (100%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]|Aggregated GHS information provided by 88 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|Aggregated GHS information provided by 101 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H320: Causes eye irritation [Warning Serious eye damage/eye irritation]|P201, P202, P261, P264, P271, P281, P304+P340, P305+P351+P338, P308+P313, P312, P337+P313, P403+P233, P405, and P501

Use water spray, foam, powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

Many of the fluorocarbons are good solvents of skin oil, so protective ointment should be used. /Fluorocarbons/|NEOPRENE GLOVES, PROTECTIVE CLOTHING, & EYE PROTECTION MINIMIZE RISK OF TOPICAL CONTACT. DEGREASING EFFECT ON SKIN CAN BE TREATED WITH LANOLIN OINTMENT. /FLUOROCARBONS/|FORCED AIR VENTILATION @ LEVEL OF VAPOR CONCN TOGETHER WITH USE OF INDIVIDUAL BREATHING DEVICES WITH INDEPENDENT AIR SUPPLY WILL MINIMIZE RISK OF INHALATION. LIFELINES SHOULD BE WORN WHEN ENTERING TANKS OR OTHER CONFINED SPACES. /FLUOROCARBONS/

Non-flammable

Explosive limits , vol% in air: 5.6-17.7

SUFFICIENT EXHAUST & GENERAL VENTILATION SHOULD BE PROVIDED TO KEEP VAPOR CONCN BELOW RECOMMENDED LEVELS. /FLUOROCARBONS/|INHALATION OF FLUOROCARBON VAPORS SHOULD BE AVOIDED. /FLUOROCARBONS/|Forced air ventilation at the level of vapor concentration together with the use of individual breathing devices with independent air supply will minimize the risk of inhalation. Lifelines should be worn when entering tanks or other confined spaces. /Fluorocarbons/|Enclosure of process materials and isolation of reaction vessels and proper design and operation of filling heads for packaging and shipping /are administrative controls that may be instituted to limit occupational exposure to fluorocarbons during manufacture, packaging, and use/. /Fluorocarbons/|For more Preventive Measures (Complete) data for 1,1-DICHLORO-1-FLUOROETHANE (8 total), please visit the HSDB record page.

1,1-Dichloro-1-fluoroethane is not an irritant or sensitizing to the skin, but may cause mild eye irritations.

Personal protection: self-contained breathing apparatus. Do NOT let this chemical enter the environment. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Carefully collect remainder. Then store and dispose of according to local regulations.

Separated from strong acids. Cool. Keep in a well-ventilated room. Store in an area without drain or sewer access.

On loss of containment this substance can cause serious risk of suffocation when in confined areas.

The substance is mildly irritating to the eyes. The substance may cause effects on the central nervous system and cardiovascular system. This may result in lowering of consciousness and cardiac disorders. Suffocation.

NO contact with hot surfaces.

Use closed system or ventilation.

Protective gloves.

Wear safety goggles.

Atmospheric measurements of 1,1-dichloro-1-fluoroethane concns indicate that emissions have grown from about 0.2-0.3 ktonnes/yr (1972-1990) to 6.4 ktonnes/yr in 1992(1).

RURAL/REMOTE: Whole tropospheric air samples were collected in the Arctic, from Kiruna on Dec 12, 1991 and analyzed for 1,1-dichloro-1-fluoroethane concns(1). The study found the concn was 0.08 parts/trillion volume. Compared to studies conducted in 1984, the atmospheric concn of 1,1-dichloro-1-fluoroethane did not appear to increase in the Southern Hemisphere(1). Stored air samples collected at Cape Grim, Tasmania from 1978 to 1993, have been analyzed for tropospheric changes in 1,1-dichloro-1-fluoroethane concns(2). The initial concn in Feb 1979 was 0.050 parts/trillion volume(2). From 1982 to 1991, the average concn of 1,1-dichloro-1-fluoroethane increased to 0.08 parts/trillion volume. However, a very sharp increase in concn began in 1992, such that it reached 0.46 parts/trillion volume by September 1993(2). Measurements based on this data indicate that emissions have grown from about 0.2-0.3 ktonnes/yr (1972-1990) to 6.4 ktonnes/yr in 1992(2). Monitoring studies have indicated that the 1,1-dichloro-1-fluoroethane global mixing ratios near the tropopause rose ten-fold from 0.09 parts/trillion volume in late 1991 to about 0.8 parts/trillion volume in late 1993(3). A global mean growth rate of 63% for the period from July 1995 to January 1997 was recorded for 1,1-dichloro-1-fluoroethane(4). Its global mean atmospheric concn in January 1997 was 5.7 parts/trillion volume(4). In October 1994, an automated GC-MS was installed at Mace Head, Ireland and analyzed atmospheric concns of 1,1-dichloro-1-fluoroethane for 30 months(5). The initial concn in Oct 1994 was approximately 5 parts/trillion, in January 1996 was 7.38 parts/trillion, and by March of 1997, the concn reached approximately 11 parts/trillion. Based on these measurements, the concn of 1,1-dichloro-1-fluoroethane increased at a rate of 2.49 parts/trillion/yr(5).

IF INHALATION OCCURS, EPINEPHRINE OR OTHER SYMPATHOMIMETIC AMINES & ADRENERGIC ACTIVATORS SHOULD NOT BE ADMIN SINCE THEY WILL FURTHER SENSITIZE HEART TO DEVELOPMENT OF ARRHYTHMIAS. /FLUOROCARBONS/|Patients with fluorohydrocarbon poisoning should not be given epinephrine (Adrenalin) or similar drugs because of the tendency of fluorohydrocarbon to induce cardiac arrhythmia, including ventricular fibrillation. /Fluorohydrocarbons/|... THE COMBINATION OF FLUOROCARBON WITH A SYMPATHOMIMETIC BRONCHODILATOR IS POTENTIALLY DANGEROUS FOR THE TREATMENT OF BRONCHIAL ASTHMA. FOR THE SAME REASON, SYMPATHOMIMETIC DRUGS ARE CONTRAINDICATED IN CARDIAC RESUSCITATION OF PATIENTS SUFFERING FROM FLUOROCARBON POISONING. /FLUOROCARBON POISONING/

LD50 Rat oral > 5000 mg/kg|LD50 Rabbit dermal > 2000 mg/kg|The 96 hr LC50 of HCFC 141b for zebra fish (brachidario rerio) was reported to be 126 mg/l in a static test using a sealed vessel.|The 48 hr EC50 for the immobilization of Daphnia magna ... using a sealed vessel, was 31.2 mg/l.|LC50 Rat inhalation 295 g/cu m/4 hr

1,1-Dichloro-1-fluoroethane's production and use as a foam blowing agent and cleaning solvent(1) may result in its release to the environment through various waste streams(SRC). Based on the Montreal Protocol, a virtual phase-out of 1,1-dichloro-1-fluoroethane is scheduled by 2020(1).

ATMOSPHERIC FATE: THEIR USE FOR AEROSOL SPRAYS WAS PROHIBITED ... BECAUSE OF THEIR DEPLETING EFFECT ON STRATOSPHERIC OZONE. /CHLOROFLUOROCARBONS/|TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 425(SRC), determined from a measured log Kow of 2.3(2) and a regression-derived equation(3), indicates that 1,1-dichloro-1-fluoroethane is expected to have moderate mobility in soil(SRC). Limited data indicate that its biodegradability in soil would be low(2). Volatilization of 1,1-dichloro-1-fluoroethane from moist soil surfaces is expected to be an important fate process(SRC) given a Henry's Law constant of 0.022 atm-cu m/mole(SRC), based upon its vapor pressure, 600 mm Hg(4), and water solubility, 420 mg/l(5). The potential for volatilization of 1,1-dichloro-1-fluoroethane from dry soil surfaces may exist(SRC) based upon a vapor pressure of 600 mm Hg(4).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 425(SRC), determined from a measured log Kow of 2.3(2) and a regression-derived equation(3), indicates that 1,1-dichloro-1-fluoroethane is expected to moderately adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon a an estimated Henry's Law constant of 0.022 atm-cu m/mole based upon its vapor pressure, 600 mm Hg(4), and water solubility, 420 mg/l(5). Using this Henry's Law constant and an estimation method(6), volatilization half-lives for a model river and model lake are 1.1 hours and 4.3 days, respectively(SRC). According to a classification scheme(7), a measured BCF of about 2(8), indicates the potential for bioconcentration in aquatic organisms is low.|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 1,1-dichloro-1-fluoroethane, which has a vapor pressure of 600 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 1,1-dichloro-1-fluoroethane is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is about 7.5 years(SRC), calculated from its rate constant of 5.9X10-15 cu cm/molecule-sec at 25 °C(3). The water solubility of 1,1-dichloro-1-fluoroethane of 420 mg/l at 25 °C(4), indicates that it may undergo atmospheric removal by wet deposition processes; however, any removed by this process is expected to rapidly revolatilize to the atmosphere(SRC).

Tropospheric lifetimes and ozone depletion potentials are estimated for all 53 possible one and two carbon hydrofluorocarbons and hydrochlorofluorocarbons. The relationships among carbon-hydrogen bond strength, activation energy for removal of hydrogen by hydroxide, trophospheric lifetime, and ozone depletion potential are examined. Algorithms are developed that are easy to apply and accurate enough for initial screening purposes. The controlling variables for determining hydrochlorofluorocarbon tropospheric lifetime include number of hydrogen atoms, molecular weight, number of carbons, number of chlorine atoms alpha and beta to hydrogen, and number of fluorine atoms beta to hydrogen. The formula presented predicts lifetimes for molecues with atmospheric lifetimes below 30 yr with a root mean square error of a factor of 2.4. An algorithm is also presented to calculate ozone depletion potential based on trophospheric lifetime; the overall root mean square error calculating ozone depletion potential from the structure of a factor of 2.5. In many cases, ozone depletion potentials of choline-containing compounds are predicted to be below 0.001. These estimates also aid in making tentative choices among alternative hydrofluorocarbons and hydrochlorofluorocarbons based on enviromental considerations.|This study investigates the impact of halocarbon use on global warming during the next century. An improved 0-dimensional computer model is used to calculate annually until 2100 the equilibrium temperature at the earth's surface as determined by halocarbons, following the expected application of specific halocarbons having a significant global warming potential. Halocarbon applications that contribute most to temperature forcing are calculated to be refrigeration and mobile air conditioning, if H(C)FCs are used unrestrictedly to replace CFCs and halons. The gases that are expected to contribute most to calculated temperature forcing are hydrochlorofluorocarbon 22 and HFC 134a. If hydrochlorofluorocarbons are phased-out to protect the ozone layer and replaced by HFCs, HFC 134a, 143a and 125 will be the most important contributors to global warming, being mainly emitted from refrigeration and mobile air conditioning appliances.|The rate constant for the vapor-phase reaction of 1,1-dichloro-1-fluoroethane with photochemically-produced hydroxyl radicals is 5.9X10-15 cu cm/molecule-sec at 25 °C(1). This corresponds to an atmospheric half-life of about 7.5 years at an atmospheric concn of 5X10+5 hydroxyl radicals per cu cm(SRC). A base-catalyzed second-order hydrolysis rate constant of 7,4X10-9 L/mole-sec(SRC) was estimated using a structure estimation method(2); this corresponds to half-lives of 2.9X10+7 years and 2.9X10+6 years at pH values of 7 and 8, respectively(2). 1,1-Dichloro-1-fluoroethane is not expected to undergo direct photolysis due to the lack of absorption in the environmental UV spectrum (>290 nm)(3).

The bioaccumulation of 1,1-dichloro-1-fluoroethane was determined in semistatic studies using zebra fish(1). Fish were exposed to concns ranging from 7.3 to 9.5 mg/l. The mean concn in zebra fish after 0.125, 1, 3, 5 and 7 days of exposure were 17, 17, 13, 16, and 18 mg/kg wet weight, respectively. A comparison of measured concns in fish and water revealed a bioaccumulation factor of 2(1). During a second bioaccumulation test using higher concns of 1,1-dichloro-1-fluoroethane, researchers found that the bioaccumulation factor was <2.5 and 2.6 after 5 and 7 days of exposure, respectively. According to a classification scheme(2), these BCF values suggest the potential for bioconcentration in aquatic organisms is low.

The Koc of 1,1-dichloro-1-fluoroethane is estimated as 425(SRC), using a measured log Kow of 2.3(1)and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 1,1-dichloro-1-fluoroethane is expected to have moderate mobility in soil.

The Henry's Law constant for 1,1-dichloro-1-fluoroethane is estimated as 0.0220 atm-cu m/mole(SRC) based upon its vapor pressure, 600 mm Hg(1), and water solubility, 420 mg/l(2). This Henry's Law constant indicates that 1,1-dichloro-1-fluoroethane is expected to volatilize rapidly from water surfaces(3). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(3) is estimated as 1.1 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(3) is estimated as 4.3 days(SRC). 1,1-Dichloro-1-fluoroethane's estimated Henry's Law constant(1,2) indicates that volatilization from moist soil surfaces may occur(SRC). 1,1-Dichloro-1-fluoroethane would be expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 600 mm Hg(1).

Occupational exposure to 1,1-dichloro-1-fluoroethane may occur through inhalation and dermal contact with this compound at workplaces where 1,1-dichloro-1-fluoroethane is produced or used. (SRC)

... MAIN FACTOR AFFECTING FATE OF FLUOROCARBONS IS BODY FAT, WHERE THEY ARE CONCENTRATED & SLOWLY RELEASED INTO BLOOD @ CONCN THAT SHOULD NOT CAUSE ANY RISK OF CARDIAC SENSITIZATION. /FLUOROCARBONS/|THERE IS A SIGNIFICANT ACCUMULATION OF FLUOROCARBONS IN BRAIN, LIVER & LUNG COMPARED TO BLOOD LEVELS, SIGNIFYING A TISSUE DISTRIBUTION OF FLUOROCARBONS SIMILAR TO THAT OF CHLOROFORM. /FLUOROCARBONS/|Absorption of fluorocarbons is much lower after oral ingestion (35-48 times) than after inhalation. ... The lung generally has the highest fluorocarbon concentrations on autopsy. /Fluorocarbons/|Although fluorocarbons cause cardiac sensitization in certain animal species, rapid elimination prevents the development of cardiotoxic concentrations from aerosol bronchodilator use except at exceedingly high doses (12 to 24 doses in 2 minutes). /Fluorocarbons/|FLUOROCARBON COMPOUNDS ARE LIPID-SOLUBLE AND THUS ARE GENERALLY WELL ABSORBED THROUGH LUNG. ABSORPTION AFTER INGESTION IS 35 TO 48 TIMES LOWER THAN AFTER INHALATION. ... FLUOROCARBONS ARE ELIMINATED BY WAY OF LUNG. /FLUOROCARBON COMPOUNDS/

A single fluorinated urinary metabolite, identified as 2,2-dichloro-2-fluoro-ethyl glucuronide, was found in rats exposed to HCFC 141b (56 g/cu m) in air for 2 hr. The metabolism was reported to be similar to that of its chlorinated analogue 1,1,1-trichloroethane, which is metabolized to 2,2,2-trichloroethanol and excreted as it glucuronate conjugate and as trichloroacetic acid.|In a pilot study for absorption and metabolism of HCFC 141b, seven groups of five male rats were exposed to the vapor by inhalation in a closed loop exposure system (concentrations ranging from 0.4 to 12 g/cu m). No metabolism was detected but the sensitivity of the method is such that it will not detect metabolism below 0.15%.|Human subjects were exposed by inhalation to 250, 500, and 1000 ppm 1,1-dichloro-1-fluoroethane (HCFC-141b) for 4 hr, and urine samples were collected from 0-4, 4-12, and 12-24 hr for metabolite analysis. 'OF nuclear magnetic resonance spectroscopic analysis of urine samples from exposed subjects showed that 2,2-dichloro-2-fluoroethyl glucuronide and dichlorofluoroacetic acid were the major and minor metabolites, respectively, of 1,1-dichloro-1-fluoroethane. Urinary 2,2-dichloro-2-fluoroethyl glucuronide was hydrolyzed to 2,2-dichloro-2-fluoroethanol by incubation with beta-glucuronidase, and the released 2,2-dichloro-2-fluoroethanol was quantified by gas chromatography/mass spectrometry. Concentrations of 2,2-dichloro-2-fluoroethanol were highest in the urine samples collected 4-12 hr after exposure, but 2,2-dichloro-2-fluoroethanol was also detected in the samples collected 0-4 and 12-24 hr after exposure. Exposure concentration-dependent excretion of 2,2-dichloro-2-fluoroethanol, obtained by hydrolysis of 2,2-dichloro-2-fluoroethyl glucuronide, was observed in seven of the eight subjects studied. In conclusion, 1,1-dichloro-1-fluoroethane is metabolized in human subjects to 2,2-dichloro-2-fluoroethanol, which is conjugated with glucuronic acid and excreted as its glucuronide in urine in a time- and exposure concentration-dependent manner.

Fresh air, rest. Refer for medical attention.

Rinse and then wash skin with water and soap.

Rinse with plenty of water (remove contact lenses if easily possible).

... Emergency treatment is supportive & includes decontamination, oxygen, & any specific therapy required in a particular case such as antiarrhythmics or anticonvulsants. A few patients may require intermittent positive-pressure ventilation, dialysis, or treatment for hepatic failure. /Solvent abuse/|... In persons who are intoxicated with fluorocarbons, steps can be taken to lessen the risk of arrhythmias. ... Before evaluation at the hospital, patients should be advised to avoid strenuous exercise. In the hospital, patients can be placed in a quiet, nonthreatening environment & sedated if necessary. If hypoxic, oxygen should be administered & metabolic abnormalities corrected. Sympathomimetic drugs should be avoided. Ventricular arrhythmias are best treated with beta-blocking agents. /Fluorocarbons/|Patients with fluorohydrocarbon poisoning should not be given epinephrine (Adrenalin) or similar drugs because of the tendency of fluorohydrocarbon to induce cardiac arrhythmia, including ventricular fibrillation. /Fluorohydrocarbons/|Victims of freon inhalation require management for hypoxic, CNS anesthetic, & cardiac symptoms. Patients must be removed from the exposure environment, & high-flow supplemental oxygen should be utilized. The respiratory system should be evaluated for injury, aspiration, or pulmonary edema & treated appropriately. CNS findings should be treated supportively. A calm environment with no physical exertion is imperative to avoid increasing endogenous adrenergic levels. Exogenous adrenergic drugs must not be used to avoid inducing sensitized myocardial dysrhythmias. Atropine is ineffective in treating bradyarrhythmias. For ventricular dysrhythmias, diphenylhydantoin & countershock may be effective. Cryogenic dermal injuries should be treated by water bath rewarming at 40-42 °C until vasodilatory flush has returned. Elevation of the limb & standard frostbite management with late surgical debridement should be utilized. Ocular exposure requires irrigation & slit-lamp evaluation for injury. /Freons/|... IF INHALATION OCCURS, EPINEPHRINE OR OTHER SYMPATHOMIMETIC AMINES & ADRENERGIC ACTIVATORS SHOULD NOT BE ADMIN SINCE THEY WILL FURTHER SENSITIZE HEART TO DEVELOPMENT OF ARRHYTHMIAS. /FLUOROCARBONS/

No adverse effects in man have been reported.|EXCESSIVE SKIN CONTACT WITH LIQ FLUOROCARBONS SHOULD BE MINIMIZED TO PREVENT DEFATTING OF SKIN ... /FLUOROCARBONS/|FLUOROCARBON VAPORS ARE 4 TO 5 TIMES HEAVIER THAN AIR. THUS HIGH CONCN TEND TO ACCUMULATE IN LOW-LYING AREAS, RESULTING IN HAZARD OF INHALATION OF CONCENTRATED VAPORS, WHICH MAY BE FATAL. /FLUOROCARBONS/|UNDER CERTAIN CONDITIONS, FLUOROCARBON VAPORS MAY DECOMPOSE ON CONTACT WITH FLAMES OR HOT SURFACES, CREATING POTENTIAL HAZARD OF INHALATION OF TOXIC DECOMPOSITION PRODUCTS. /FLUOROCARBONS/|For more Human Toxicity Excerpts (Complete) data for 1,1-DICHLORO-1-FLUOROETHANE (10 total), please visit the HSDB record page.

1,1-dichloro-1-fluoroethane

The substance can be absorbed into the body by inhalation.

Drowsiness. Confusion. Unconsciousness.

Redness. Pain.

Redness. Pain.

All other chemical product and preparation manufacturing|Ethane, 1,1-dichloro-1-fluoro-: ACTIVE|PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.|Near-term substitute for CFC-11 (blowing agent and refrigerant).

GAS CHROMATOGRAPHIC METHOD FOR MEASURING HALOCARBONS IN AMBIENT AIR SAMPLES IS PRESENTED. /HALOCARBONS/|FLUOROCARBONS IN AIR OF WORKING AREA & IN EXHALED AIR CAN BE ANALYZED BY IR SPECTROMETRY. /FLUOROCARBONS/|GAS CHROMATOGRAPHIC METHOD IS PRESENTED FOR FREONS. /FREONS/

GAS CHROMATOGRAPHIC METHOD FOR DETERMINING FLUOROCARBONS IS DESCRIBED. CONCN IN BODY FLUIDS ARE DETERMINED BY MEANS OF HEAD SPACE ANALYSIS. /FLUOROCARBONS/|FLUOROCARBON DETERMINATION IN BLOOD: GAS CHROMATOGRAPHY WITH ELECTRON CAPTURE DETECTION. /FLUOROCARBONS/