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Nocardicin A

Nocardicin A structure

Nocardicin A 

structure
  • CAS No:

    39391-39-4

  • Formula:

    C23H24N4O9

  • Chemical Name:

    Nocardicin A

  • Synonyms:

    1-Azetidineacetic acid,3-[[(2Z)-2-[4-[(3R)-3-amino-3-carboxypropoxy]phenyl]-2-(hydroxyimino)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-,(αR,3S)-;1-Azetidineacetic acid,3-[[[4-(3-amino-3-carboxypropoxy)phenyl](hydroxyimino)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-,[3S-[1(S*),3R*[Z(S*)]]]-;1-Azetidineacetic acid,3-[[(2Z)-[4-[(3R)-3-amino-3-carboxypropoxy]phenyl](hydroxyimino)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-,(αR,3S)-;(αR,3S)-3-[[(2Z)-2-[4-[(3R)-3-Amino-3-carboxypropoxy]phenyl]-2-(hydroxyimino)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid;Antibiotic FR 1923;Nocardicin A;59508-80-4

Description

Nocardicin A is a dicarboxylic acid, a D-serine derivative, a D-alpha-amino acid and a nocardicin. It is a conjugate acid of a nocardicin A(1-) and a nocardicin A(2-).

Nocardicin A Basic Attributes

500.45806

500.46

R76HLW7Z19

Characteristics

1.4360

211-214 °C (decomp)

591.34°C (rough estimate)

1.6500 (estimate)

LD50 in male mice, rats (mg/kg): >8000 orally; >2000 i.v.; 2500, 2600 i.p. (Aoki)

Drug Information

nocarcidins

Nocardicin A Use and Manufacturing

Nocardicin A is a β-lactam antibiotic.

Computed Properties

Molecular Weight:500.5
XLogP3:-1.1
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:11
Exact Mass:500.15432836
Monoisotopic Mass:500.15432836
Topological Polar Surface Area:212
Heavy Atom Count:36
Complexity:851
Defined Atom Stereocenter Count:3
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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