ECOPLADIBUM
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ECOPLADIBUM
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CAS No:
381683-92-7
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Formula:
C39H33Cl3N2O5S
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Chemical Name:
ECOPLADIBUM
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Synonyms:
ECOPLADIBUM;4-(2-(5-chloro-2-(2-(((3,4-dichlorobenzyl)sulfonyl)aMino)ethyl)-1-(diphenylMethyl)-1H-indol-3-yl)ethoxy)benzoic acid;Ecopladib;Ecopladib (PLA 725);PLA 725;Benzoic acid, 4-[2-[5-chloro-2-[2-[[[(3,4-dichlorophenyl)methyl]sulfonyl]amino]ethyl]-1-(diphenylmethyl)-1H-indol-3-yl]ethoxy]-
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CAS No:
Description
Ecopladib is an indole inhibitor of cytosolic phospholipase A2alpha (cPLA2alpha, type IVA phospholipase) with antiinflammatory activity.
Characteristics
106.01000
10.69270
1.35±0.1 g/cm3
124-125 °C
912.3±75.0 °C(Predicted)
505.5ºC
1.646
4.46±0.10
Drug Information
Compounds that inhibit or block the activity of a PHOSPHOLIPASE A2 enzyme. (See all compounds classified as Phospholipase A2 Inhibitors.)
4-(2-(5-chloro-2-(2-(((3,4-dichlorobenzyl)sulfonyl)amino)ethyl)-1-(diphenylmethyl)-1H-indol-3-yl)ethoxy)benzoic acid
Computed Properties
Molecular Weight:748.1
XLogP3:9.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:14
Exact Mass:746.117576
Monoisotopic Mass:746.117576
Topological Polar Surface Area:106
Heavy Atom Count:50
Complexity:1150
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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