c-GpAp
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c-GpAp
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CAS No:
849214-04-6
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Formula:
C20H24N10O13P2
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Chemical Name:
c-GpAp
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Synonyms:
c-GpAp;di-GAMP;di-cGAMP;cGAMP (Cyclic GMP-AMP;3''-Guanylic acid, adenylyl-(3''?5'')-, cyclic nucleotide;3',3'-Cyclic guanosine monophosphate-adenosine monophosphate;cGAMP;3'3'-cGAMP
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CAS No:
Description
C-GMP-AMP is a cyclic purine dinucleotide that consists of AMP and GMP units cyclised via 3',5'-linkages. It is an adenyl ribonucleotide, a cyclic purine dinucleotide and a guanyl ribonucleotide. It is a conjugate acid of a c-GMP-AMP(2-).
c-GpAp Use and Manufacturing
c-GpAp induces the production of interferons, a usual response to triggers in the cytoplasm of mammalian cells by the presence of DNA.
Computed Properties
Molecular Weight:674.4
XLogP3:-5.9
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:19
Rotatable Bond Count:2
Exact Mass:674.09995485
Monoisotopic Mass:674.09995485
Topological Polar Surface Area:325
Heavy Atom Count:45
Complexity:1300
Defined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes