 Home > Encyclopedia > Salbutamol EP Impurity B

Salbutamol EP Impurity B

Salbutamol EP Impurity B structure

CAS No:
96948-64-0
Formula:
C12H19NO2
Chemical Name:
Salbutamol EP Impurity B
Synonyms:
t-Butylnorsynephrine;2-tert-Butylamino-1-(4-hydroxyphenyl)ethanol;Salbutamol EP Impurity B;4-[2-(tert-Butylamino)-1-hydroxyethyl]phenol;Salbutamol Impurity 2（Salbutamol EP Impurity B）;Salbutamol EP Imp B;Imp. B (EP):(1RS)-2-[(1,1-Dimethylethyl)-amino]-1-(4-hydroxyphenyl)ethano;Benzenemethanol, α-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-
Categories:
Organic Chemistry > Amides

Request for Quotation

Salbutamol EP Impurity B Basic Attributes

Molecular Weight：

209.28

Exact Mass：

209.28

Color/Form：

Off-White

Characteristics

PSA：

52.5 Å²

Density：

1.079±0.06 g/cm3(Predicted)

Melting Point：

172-173.5 °C

Boiling Point：

361.8±27.0 °C(Predicted)

PKA：

9.97±0.26(Predicted)

Critical Temperature & Pressure：

Hygroscopic, Refrigerator, under inert atmosphere

Safety Information

wgk germany：

WGK 3

GHS Classification：

|Warning|H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

KWD 2066

Salbutamol EP Impurity B Use and Manufacturing

t-Butylnorsynephrine is a derivative of norsynephrine, an endogenous biogenic amine that is closely related to norepinephrine, which has effects on the adrenergic and dopaminergic system. Structure and activity tudies have shown that t-Butylnorsynephrine may also exhibit effects towards β-adrenergic receptors and β-adrenergic receptor-coupled adenylate cyclase.

Computed Properties

Molecular Weight:209.28
XLogP3:0.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:209.141578849
Monoisotopic Mass:209.141578849
Topological Polar Surface Area:52.5
Heavy Atom Count:15
Complexity:181
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes