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Home > Encyclopedia > 1-(4-Hydroxyphenyl)piperazine

1-(4-Hydroxyphenyl)piperazine

1-(4-Hydroxyphenyl)piperazine structure

1-(4-Hydroxyphenyl)piperazine 

structure
  • CAS No:

    56621-48-8

  • Formula:

    C10H14N2O

  • Chemical Name:

    1-(4-Hydroxyphenyl)piperazine

  • Synonyms:

    Phenol,4-(1-piperazinyl)-;4-(1-Piperazinyl)phenol;1-(4-Hydroxyphenyl)piperazine;N-(4-Hydroxyphenyl)piperazine;4-(4-Hydroxyphenyl)piperazine;4-Piperazinophenol

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

1-(4-Hydroxyphenyl)piperazine Basic Attributes

178.23100

178.23

260-289-6

DTXSID80205197

2933599090

Characteristics

35.50000

1.19560

Brown Powder

1.141 g/cm3

218-220 °C @ Solvent: Ethanol, Water

371.3ºC at 760 mmHg

178.3ºC

1.576

Safety Information

III

8

UN3263

3

R36/37/38

S26-S36

Xi

|Warning|H315 (91.11%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 47 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

1-(4-hydroxyphenyl)piperazine is a known human metabolite of 1-(4-methoxyphenyl)piperazine.

Computed Properties

Molecular Weight:178.23
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:178.110613074
Monoisotopic Mass:178.110613074
Topological Polar Surface Area:35.5
Heavy Atom Count:13
Complexity:149
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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