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Mepindolol

Mepindolol structure

CAS No:
23694-81-7
Formula:
C15H22N2O2
Chemical Name:
Mepindolol
Synonyms:
2-Propanol,1-[(1-methylethyl)amino]-3-[(2-methyl-1H-indol-4-yl)oxy]-;2-Propanol,1-(isopropylamino)-3-[(2-methylindol-4-yl)oxy]-;1-[(1-Methylethyl)amino]-3-[(2-methyl-1H-indol-4-yl)oxy]-2-propanol;Mepindolol;(±)-Mepindolol;Racemic Mepindolol;1-[Isopropylamino]-3-[(2-methyl-indol-4-yl)oxy]-2-propanol;99603-84-6
Categories:
Organic Chemistry > Amides

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Description

Mepindolol is a member of indoles.|Mepindolol is a 2-methyl derivative of pindolol. It is a beta blocker.

Mepindolol Basic Attributes

Molecular Weight：

262.34700

Exact Mass：

262.35

EC Number：

245-831-1

ATC Code：

C - Cardiovascular system

HScode：

2933990090

Characteristics

PSA：

57.28000

XLogP3：

2.60490

Density：

1.131g/cm3

Melting Point：

95-97 °C

Boiling Point：

469.9ºC at 760mmHg

Flash Point：

238ºC

Refractive Index：

1.59

Vapor Pressure：

1.24E-09mmHg at 25°C

Drug Information

MeSH：

Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. (See all compounds classified as Adrenergic beta-Antagonists.)

MeSH Entry Terms：

1-(isopropylamino)-3-(2-methylindol-4-yloxy)-2-propanol sulfate

Mepindolol Use and Manufacturing

Use Classification：

Pharmaceuticals

Computed Properties

Molecular Weight:262.35
XLogP3:2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:262.168127949
Monoisotopic Mass:262.168127949
Topological Polar Surface Area:57.3
Heavy Atom Count:19
Complexity:273
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes