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Tymazoline

Tymazoline structure

Tymazoline 

structure
  • CAS No:

    24243-97-8

  • Formula:

    C14H20N2O

  • Chemical Name:

    Tymazoline

  • Synonyms:

    1H-Imidazole,4,5-dihydro-2-[[5-methyl-2-(1-methylethyl)phenoxy]methyl]-;2-Imidazoline,2-[(thymyloxy)methyl]-;4,5-Dihydro-2-[[5-methyl-2-(1-methylethyl)phenoxy]methyl]-1H-imidazole;2-(Thymyloxymethyl)glyoxalidine;Tymazoline;Pernazene;2-((2-Isopropyl-5-methylphenoxy)methyl)-4,5-dihydro-1H-imidazole

Description

Solid


Tymazoline is a monoterpenoid.|Tymazoline is a nasal preparation.

Tymazoline Basic Attributes

232.32100

232.32

U993RH5585

DTXSID40178939

R - Respiratory system

2933290090

Characteristics

33.62000

2.26330

1.08g/cm3

413.4ºC

203.8ºC

1.556

1.15E-06mmHg at 25°C

Toxicity

A large overdose or accidental oral intake, especially in children, may cause excessive sedation with drowsiness, reduced body temperature, heart rate relief and fluctuations in blood pressure and collapse.

Drug Information

For the treatment of Inflammation of the lining of the nose and paranasal sinuses and allergic inflammation of nasopharyngeal.

Tymazoline is a drug with antihistaminic and sympathomimetic properties. It locally reduces swelling, inflammation and mucosal secretions of the nasal passages.

Thymazen causes vasoconstriction of the nasal mucosa, reducing congestion and thus the swelling of the mucosa. Also reduces the secretions from the nose. Thymazen acts on alpha-adrenergic receptors, which reduces local inflammation of the nasal mucosa especially if their cause is an allergy.

Computed Properties

Molecular Weight:232.32
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:232.157563266
Monoisotopic Mass:232.157563266
Topological Polar Surface Area:33.6
Heavy Atom Count:17
Complexity:275
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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