NG-Nitro-L-arginine methyl ester
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NG-Nitro-L-arginine methyl ester
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CAS No:
50903-99-6
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Formula:
C7H15N5O4
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Chemical Name:
NG-Nitro-L-arginine methyl ester
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Synonyms:
L-Ornithine,N5-[imino(nitroamino)methyl]-,methyl ester;Nω-Nitro-L-arginine methyl ester;N-Nitro-L-arginine methyl ester;NG-Nitro-L-arginine methyl ester;L-NAME;L-NAME;NAME;Nω-Nitro-L-arginine methyl ester;NG-Nitro-L-arginine Me ester;126265-24-5;162715-84-6;189639-12-1;944269-22-1;952702-20-4
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CAS No:
Description
N(gamma)-nitro-L-arginine methyl ester is an alpha-amino acid ester that is the methyl ester of N(gamma)-nitro-L-arginine. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is an alpha-amino acid ester, a L-arginine derivative, a N-nitro compound and a methyl ester. It is a conjugate base of a N(gamma)-nitro-L-arginine methyl ester(1+).|L-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury.|A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.
Drug Information
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)
L-NAME
Computed Properties
Molecular Weight:233.23
XLogP3:-1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:233.11240398
Monoisotopic Mass:233.11240398
Topological Polar Surface Area:149
Heavy Atom Count:16
Complexity:274
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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