Fentiazac
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Fentiazac
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CAS No:
18046-21-4
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Formula:
C17H12ClNO2S
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Chemical Name:
Fentiazac
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Synonyms:
5-Thiazoleacetic acid,4-(4-chlorophenyl)-2-phenyl-;5-Thiazoleacetic acid,4-(p-chlorophenyl)-2-phenyl-;4-(4-Chlorophenyl)-2-phenyl-5-thiazoleacetic acid;2-Phenyl-4-p-chlorophenylthiazol-5-ylacetic acid;BR 700;4-(4-Chlorophenyl)-2-phenylthiazole-5-acetic acid;Fentiazac;Norvedan;CH 800;4-(p-Chlorophenyl)-2-phenylthiazole-5-acetic acid;BR 700 (pharmaceutical);WY 21894;Donorest;Flogene;NSC 282191;[4-(4-Chlorophenyl)-2-phenylthiazol-5-yl]acetic acid;2-(4-(4-Chlorophenyl)-2-phenylthiazol-5-yl)acetic acid
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CAS No:
Fentiazac Basic Attributes
329.80100
329.80
241-958-1
0YHF6E6NLS
282191
DTXSID8023050
M - Musculo-skeletal system
Characteristics
78.43000
4.75760
1.451 g/cm3
161.5 °C
556.2ºC at 760mmHg
290.2ºC
1.646
1.09e-05 M
3.3E-13mmHg at 25°C
Drug Information
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)
2-phenyl-4-(p-chlorophenyl)thiazol-5-ylacetic acid
Computed Properties
Molecular Weight:329.8
XLogP3:5.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:329.0277275
Monoisotopic Mass:329.0277275
Topological Polar Surface Area:78.4
Heavy Atom Count:22
Complexity:381
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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