Stepronin
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Stepronin
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CAS No:
72324-18-6
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Formula:
C10H11NO4S2
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Chemical Name:
Stepronin
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Synonyms:
Glycine,N-[1-oxo-2-[(2-thienylcarbonyl)thio]propyl]-;N-[1-Oxo-2-[(2-thienylcarbonyl)thio]propyl]glycine;Prostenoglycine;Stepronin;Tiase;Bronco-plus;TTPG
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CAS No:
Description
Solid
Stepronin is a N-acyl-amino acid.|Strepronin is a mucolytic drug. A mucolytic agent is any agent which dissolves thick mucus usually used to help relieve respiratory difficulties. The viscosity of mucous secretions in the lungs is dependent upon the concentrations of mucoprotein as well as the presence of disulfide bonds between these macromolecules and DNA.
Characteristics
137.01000
1.60170
White or off white crystalline
1.428 g/cm3
168-170 °C
521.2ºC at 760 mmHg
269ºC
1.609
2.11e-01 g/L
Store in original container in a cool dark place.
Drug Information
Strepronin is a mucolytic (expectorant) drug.
The drug promotes drainage of mucus from the lungs by thinning the mucus and lubricating the irritated respiratory tract
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)|Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging. (See all compounds classified as Immunosuppressive Agents.)|Agents that increase mucous excretion. Mucolytic agents, that is drugs that liquefy mucous secretions, are also included here. (See all compounds classified as Expectorants.)
An expectorant increases bronchial secretions and mucolytics help loosen thick bronchial secretions. Expectorants reduce the thickness or viscosity of bronchial secretions thus increasing mucus flow that can be removed more easily through coughing, Mucolytics break down the chemical structure of mucus molecules. The mucus becomes thinner and can be removed more easily through coughing.
2-(alpha-thenoylthio)propionylglycine
Computed Properties
Molecular Weight:273.3
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:273.01295018
Monoisotopic Mass:273.01295018
Topological Polar Surface Area:137
Heavy Atom Count:17
Complexity:321
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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