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Pyoluteorin

Pyoluteorin structure

Pyoluteorin 

structure
  • CAS No:

    25683-07-2

  • Formula:

    C11H7Cl2NO3

  • Chemical Name:

    Pyoluteorin

  • Synonyms:

    Methanone,(4,5-dichloro-1H-pyrrol-2-yl)(2,6-dihydroxyphenyl)-;Ketone,4,5-dichloropyrrol-2-yl 2,6-dihydroxyphenyl;Pyoluteorin;(4,5-Dichloro-1H-pyrrol-2-yl)(2,6-dihydroxyphenyl)methanone;NSC 143092

Description

Pyoluteorin is a member of the class of resorcinols that is resorcinol in which the hydrogen at position 2 is replaced by a 4,5-dichloro-1H-pyrrole-2-carbonyl group. It is a natural product found in Pseudomonas fluorescens which exhibits antibacterial properties and is a strong inducer of caspase-3-dependent apoptosis. It has a role as a bacterial metabolite, an apoptosis inducer, an antifungal agent, a marine metabolite and an antibacterial agent. It is a member of resorcinols, a member of pyrroles, an organochlorine compound, a diol, a beta-hydroxy ketone, a polyketide, an aromatic ketone and an organochlorine pesticide.

Pyoluteorin Basic Attributes

272.08 g/mol

272.08

143092

DTXSID30180384

Characteristics

73.3 Ų

174-175 °C (decomp)

Drug Information

pyoluteorin

Computed Properties

Molecular Weight:272.08
XLogP3:3.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:270.9802985
Monoisotopic Mass:270.9802985
Topological Polar Surface Area:73.3
Heavy Atom Count:17
Complexity:292
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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