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Trimazosin

Trimazosin structure

Trimazosin 

structure
  • CAS No:

    35795-16-5

  • Formula:

    C20H29N5O6

  • Chemical Name:

    Trimazosin

  • Synonyms:

    1-Piperazinecarboxylic acid,4-(4-amino-6,7,8-trimethoxy-2-quinazolinyl)-,2-hydroxy-2-methylpropyl ester;Trimazosin;2-Hydroxy-2-methylpropyl 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate

Description

Trimazosin is a N-arylpiperazine.|Trimazosin is a sympatholytic alpha blocker.

Trimazosin Basic Attributes

435.5 g/mol

435.47

252-732-7

31L760807H

DTXSID50189319

C - Cardiovascular system

Characteristics

133 Ų

158-159 °C

Drug Information

Drugs that bind to and block the activation of ADRENERGIC ALPHA-1 RECEPTORS. (See all compounds classified as Adrenergic alpha-1 Receptor Antagonists.)|Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)|Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)

2-hydroxy-2-methylpropyl 4-(4-amino-6,7,8-trimethoxy-2-quinqzolinyl)-1-piperazinecar boxylate

Computed Properties

Molecular Weight:435.5
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:7
Exact Mass:435.21178366
Monoisotopic Mass:435.21178366
Topological Polar Surface Area:133
Heavy Atom Count:31
Complexity:603
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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