Proxicromil
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Proxicromil
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CAS No:
60400-92-2
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Formula:
C17H18O5
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Chemical Name:
Proxicromil
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Synonyms:
4H-Naphtho[2,3-b]pyran-2-carboxylic acid,6,7,8,9-tetrahydro-5-hydroxy-4-oxo-10-propyl-;6,7,8,9-Tetrahydro-5-hydroxy-4-oxo-10-propyl-4H-naphtho[2,3-b]pyran-2-carboxylic acid;Proxicromil
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CAS No:
Drug Information
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)
FPL 57787
Computed Properties
Molecular Weight:302.32
XLogP3:4.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:302.11542367
Monoisotopic Mass:302.11542367
Topological Polar Surface Area:83.8
Heavy Atom Count:22
Complexity:497
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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