4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol;hydrochloride
-
![4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol;hydrochloride structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220811/6dadc746c0924dd49a67d14f57aa7029.png "4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol;hydrochloride")
4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol;hydrochloride
structure -
-
CAS No:
125251-66-3
-
Formula:
C18H24ClNO4
-
Chemical Name:
4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol;hydrochloride
-
Synonyms:
arbutamine;arbutamine hydrochloride;arbutamine hydrochloride, (R)-isomer;GenESA;Arbutamine hydrochloride;Genesa;UNII-K0NF2CPJ7F;Arbutamine hydrochloride [USAN];K0NF2CPJ7F;125251-66-3;(R)-3,4-Dihydroxy-alpha-(((4-(p-hydroxyphenyl)butyl)amino)methyl)benzyl alcohol hydrochloride;GP-2-121-3;Arbutamine hydrochloride (USAN);Arbutamine HCl;Genesa (TN);SCHEMBL40757;CHEMBL1200385;DTXSID40154718;1,2-Benzenediol, 4-(1-hydroxy-2-((4-(4-hydroxyphenyl)butyl)amino)ethyl)-, (R)-hydrochloride;1,2-Benzenediol, 4-(1-hydroxy-2-((4-(4-hydroxyphenyl)butyl)amino)ethyl)-, (R)-, hydrochloride;D02976;Q27281787
-
CAS No:
Description
Arbutamine Hydrochloride is the hydrochloride salt form of arbutamine, a synthetic catecholamine with positive chronotropic and inotropic properties, used in echocardiography and diagnostic coronary angiography. Arbutamine binds to and activates beta-1 adrenergic receptors in the myocardium, thereby increasing heart rate and increasing force of myocardial contraction. By exerting a chronotropic and inotropic effect, arbutamine mimics the cardiac stress caused by exercise that may prevent adequate tissue perfusion and oxygenation, and may provoke myocardial ischemia in patients with coronary artery disease.
4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol;hydrochloride Basic Attributes
353.8 g/mol
353.1393859 g/mol
K0NF2CPJ7F
DTXSID40154718
C65239
Drug Information
Drugs that selectively bind to and activate beta-adrenergic receptors. (See all compounds classified as Adrenergic beta-Agonists.)|Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)
arbutamine
4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol;hydrochloride Use and Manufacturing
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:353.8
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:353.1393859
Monoisotopic Mass:353.1393859
Topological Polar Surface Area:93
Heavy Atom Count:24
Complexity:320
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Request for Quotation