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hernandonine

hernandonine structure

hernandonine 

structure
  • CAS No:

    28314-78-5

  • Formula:

    C18H9NO5

  • Chemical Name:

    hernandonine

  • Synonyms:

    [1,3]dioxolo[4',5':4,5]benzo[1,2,3-de][1,3]dioxolo[4',5':5,6]benzo[1,2-g]quinolin-8-one; 11H-bis[1,3]benzodioxolo[6,5,4-de:4',5'-g]quinolin-11-one; 8H-Bis(1,3)benzodioxolo(6,5,4-de:4',5'-g)quinolin-8-one; 11H-[1,3]Benzodioxolo[6,5,4-de]-1,3-benzodioxolo[4,5-g]quinolin-11-one;

Description

Hernandonine is an oxoaporphine alkaloid isolated from Hernandia ovigera and Lindera chunii and has been shown exhibit inhibitory activity against HIV-1 integrase. It has a role as a metabolite and a HIV-1 integrase inhibitor. It is an organic heterohexacyclic compound, an oxacycle, a cyclic ketone and an oxoaporphine alkaloid.

hernandonine Basic Attributes

319.26800

319.04807239 g/mol

DTXSID90182561

Characteristics

66.88000

2.90360

1.641g/cm3

617.7ºC at 760mmHg

327.3ºC

1.787

3.48E-15mmHg at 25°C

Drug Information

11H-(1,3)Benzodioxolo(6,5,4-de)-1,3-benzodioxolo(4,5-g)quinolin-11-one

Computed Properties

Molecular Weight:319.3
XLogP3:3.2
Hydrogen Bond Acceptor Count:6
Exact Mass:319.04807239
Monoisotopic Mass:319.04807239
Topological Polar Surface Area:66.9
Heavy Atom Count:24
Complexity:556
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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