2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
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![2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220811/f5396e483a0b40a0983fa4a34fded502.png "2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one")
2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
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CAS No:
419547-11-8
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Formula:
C25H17ClN4O3
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Chemical Name:
2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
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Synonyms:
2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)pyrazolo(1,5-a)pyrimidin-7(4H)-one;3-(4-chlorophenyl)-5-(4-nitrophenyl)-2-(phenylmethyl)pyrazolo(1,5-a)pyrimidin-7(4H)-one;NAV-2729;NAV2729;NAV-2729;419547-11-8;2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one;CHEMBL3716578;NAV 2729;2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one;NAV2729;NAV-2729Grassofermata;Oprea1_305395;SCHEMBL13516218;CHEBI:132811;AMY23749;EX-A2011;BDBM50168142;AKOS030211129;ZINC106616565;BS-16805;HY-112473;CS-0046101;2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)-4H-pyrazolo[1,5-a]pyrimidin-7-one;C1=CC([N+](=O)[O-])=CC=C1C(N1)=CC(=O)N2C1=C(C=1C=CC(Cl)=CC=1)C(CC=1C=CC=CC=1)=N2
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CAS No:
Description
NAV2729 is a pyrazolopyrimidine that is 4H-pyrazolo[1,5-a]pyrimidin-7-one which is substituted at positions 2, 3, and 5 by benzyl, p-chlorophenyl, and p-nitrophenyl groups, respectively. It is an inhibitor of ADP-ribosylation factor 6 (ARF6), a member of the ADP ribosylation factor family of GTP-binding proteins. It has a role as an inhibitor. It is a pyrazolopyrimidine, a C-nitro compound and a member of monochlorobenzenes.
2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one Basic Attributes
456.9 g/mol
456.0989181 g/mol
Computed Properties
Molecular Weight:456.9
XLogP3:5.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:456.0989181
Monoisotopic Mass:456.0989181
Topological Polar Surface Area:90.5
Heavy Atom Count:33
Complexity:871
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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