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Home > Encyclopedia > 4-[(4-Amino-3-methylphenyl)amino]phenol

4-[(4-Amino-3-methylphenyl)amino]phenol

4-[(4-Amino-3-methylphenyl)amino]phenol structure

4-[(4-Amino-3-methylphenyl)amino]phenol 

structure
  • CAS No:

    6219-89-2

  • Formula:

    C13H14N2O

  • Chemical Name:

    4-[(4-Amino-3-methylphenyl)amino]phenol

  • Synonyms:

    Phenol,4-[(4-amino-3-methylphenyl)amino]-;Phenol,p-(4-amino-m-toluidino)-;4-[(4-Amino-3-methylphenyl)amino]phenol;C.I. 76565;Kayaku Sulphur Blue RP;Thional Indone Blue RN;Ursol Blue Grey OM;3′-Methyl-4′-amino-4-hydroxydiphenylamine;4-Amino-4′-hydroxy-3-methyldiphenylamine;NSC 37093

Description

PHYSICAL DESCRIPTION: Black crystalline solid. (NTP, 1992)


4-amino-4'-hydroxy-3-methyldiphenylamine is a black crystalline solid. (NTP, 1992)


4-amino-4'-hydroxy-3-methyldiphenylamine is a black crystalline solid. (NTP, 1992)

4-[(4-Amino-3-methylphenyl)amino]phenol Basic Attributes

214.26306

214.26

228-294-8

7YB07WHF8N

37093

DTXSID9024483

2922299090

Characteristics

58.3

3.68060

4-amino-4'-hydroxy-3-methyldiphenylamine is a black crystalline solid. (NTP, 1992)

1.242g/cm3

320° F (NTP, 1992)

388.2ºC at 760 mmHg

188.6ºC

1.698

less than 1 mg/mL at 68.9° F (NTP, 1992)

mic-sat 100 mLg/plate EMMUEG 19(Suppl 21),2,1992

Flammable; high temperature produces toxic nitrogen oxide fumes

This chemical is sensitive to prolonged exposure to air. Insoluble in water.

Phenols and Cresols

4-AMINO-4'-HYDROXY-3-METHYLDIPHENYLAMINE may react with strong oxidizers, mineral acids and bases. (NTP, 1992)

Safety Information

Warehouse ventilated, low temperature and dry

P264, P270, P273, P280, P301+P312, P302+P352, P305+P351+P338, P321, P330, P332+P313, P337+P313, P362, P501

H302

Flash point data concerning this compound are not available, however, it is probably combustible. (NTP, 1992)

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P273, P280, P301+P312, P302+P352, P305+P351+P338, P321, P330, P332+P313, P337+P313, P362, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Fires involving this compound can be controlled using dry chemical, carbon dioxide or Halon extinguishers. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: If a spill of this chemical occurs, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with acetone and transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should keep this material in a tightly-closed container under an inert atmosphere, and store it at refrigerated temperatures. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Drug Information

ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

4-[(4-Amino-3-methylphenyl)amino]phenol Use and Manufacturing

Methods of Manufacturing

CONDENSATION OF O-TOLUIDINE WITH P-NITROSOPHENOL IN SULFURIC ACID FOLLOWED BY REDUCTION WITH SODIUM TETRASULFIDE & HEATING OF THE RESULTING INDOPHENOL WITH AQUEOUS SODIUM POLYSULFIDE

Uses

DYE FOR CELLULOSE, LEATHER & PAPER|DYE FOR DIRECT PRINTING

Production

(1979) PROBABLY GREATER THAN 2.27X10+6 GRAMS|(1981) PROBABLY GREATER THAN 2.27X10+6 GRAMS

ESSENTIALLY 100% AS A DYE

C.I. Sulphur Blue 7: ACTIVE|Phenol, 4-[(4-amino-3-methylphenyl)amino]-: INACTIVE

Computed Properties

Molecular Weight:214.26
XLogP3:2.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:214.110613074
Monoisotopic Mass:214.110613074
Topological Polar Surface Area:58.3
Heavy Atom Count:16
Complexity:214
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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