PGF1α
-
PGF1α
structure -
-
CAS No:
745-62-0
-
Formula:
C20H36O5
-
Chemical Name:
PGF1α
-
Synonyms:
Prost-13-en-1-oic acid,9,11,15-trihydroxy-,(9α,11α,13E,15S)-;Cyclopentaneheptanoic acid,3,5-dihydroxy-2-(3-hydroxy-1-octenyl)-;Prostaglandin F1;(9α,11α,13E,15S)-9,11,15-Trihydroxyprost-13-en-1-oic acid;PGF1α;Prostaglandin F1α;9α,11α,15(S)-Trihydroxy-13-trans-prostenoic acid;U 18714;21562-44-7
-
CAS No:
Characteristics
97.99000
2.60
Solid
1.1±0.1 g/cm3
102.5°C
526.5±50.0 °C at 760 mmHg
286.3±26.6 °C
1.555
PGF1α Use and Manufacturing
Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10?11 M. PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro.