1,1,2,2-Tetrabromoethane
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1,1,2,2-Tetrabromoethane
structure -
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CAS No:
79-27-6
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Formula:
C2H2Br4
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Chemical Name:
1,1,2,2-Tetrabromoethane
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Synonyms:
Ethane,1,1,2,2-tetrabromo-;1,1,2,2-Tetrabromoethane;Acetylene tetrabromide;Muthmann's liquid;TBE;1,1,2,2-Tetrabromoethylene;NSC 406889
- Categories:
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CAS No:
Description
yellowish heavy liquid with odour of camphor and Acetylene tetrabromide is a combustible, colorless to yellow liquid. Strong odor.
Acetylene tetrabromide appears as a yellowish liquid with a pungent odor, much like camphor. Irritates skin. Ingestion or inhalation may produce irritation or a narcotic effect. Chronic exposure may damage liver. Noncombustible, but decomposes at 374°F, releasing flammable and toxic fumes. Much denser than water. Used as a solvent for fats, oils and waxes.|YELLOW HEAVY LIQUID WITH PUNGENT ODOUR.|Pale-yellow liquid with a pungent odor similar to camphor or iodoform.|Pale-yellow liquid with a pungent odor similar to camphor or iodoform. [Note: A solid below 32°F.]
Acetylene tetrabromide appears as a yellowish liquid with a pungent odor, much like camphor. Irritates skin. Ingestion or inhalation may produce irritation or a narcotic effect. Chronic exposure may damage liver. Noncombustible, but decomposes at 374°F, releasing flammable and toxic fumes. Much denser than water. Used as a solvent for fats, oils and waxes.
1,1,2,2-Tetrabromoethane Basic Attributes
345.65
345.65
201-191-5
V00GKC584O
1235
406889
2504
DTXSID1026083
Yellowish, heavy liquid /SRP: technical grade/|Colorless to yellow liquid|Pale-yellow liquid [Note: A solid below 32 degrees F].
29033036
Characteristics
0
2.8
Clear Liquid
2.9656 g/cm3 @ Temp: 20 °C
0 °C
151 °C @ Press: 54 Torr
118-120°C/15mm
1.654
H2O: 0.63 g/L (20 ºC);alcohol: miscible
Store at +15°C to +25°C.
0.1 mm Hg ( 20 °C)
11.9 (vs air)
Oral-Rat LD50: 1200 mg/kg; Oral-Mouse LD50: 269 mg/kg
High temperature combustible; decomposes toxic carbonyl bromide gas in case of heat
Odor of camphor and iodoform
1 mg/l = 70.4 ppm and 1 ppm = 14 mg/cu m @ 25 °C|ppm v/v in air "saturated" at 25 °C: 80 (theoretical)|Wt/gal @ 25 °C= 24.57 lb
Insoluble in water.
Halogenated Organic Compounds
ACETYLENE TETRABROMIDE is incompatible with strong bases and chemically active metals. Incompatible with hot iron, aluminum and zinc in the presence of steam. May react with magnesium. Softens or destroys most plastics and rubber (NTP, 1992).
635 °F (NTP, 1992)|635 °F|335 °C
Noncombustible Liquid
... Will attack some forms of plastics, rubber, and coatings.
48.7 kJ/mol at boiling point
Safety Information
III
6.1
UN 2504 6.1/PG 3
2
26-36-52/53
24-27-45-61-1/2
KI8225000
T+,T
The warehouse is ventilated, low temperature and dry; stored and transported separately from food, oxidants and acids
Toxic
Stable. Incompatible with strong oxidizing agents, aluminium, magnesium, alkali metals.
P260-P273-P284-P305 + P351 + P338-P310
H302-H315-H319-H330-H412
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.|Acetylene tetrabromide may be disposed of by absorbing it in vermiculite, dry sand, earth, or a similar material and disposing in a secured sanitary landfill.
Tetrabromoethane is chemically incompatible with active metals, strong caustics, hot iron, aluminum, or zinc in the presence of steam.|Strong caustics; hot iron; reducing metals such as aluminum, magnesium & zinc.
Excerpt from ERG Guide 159 [Substances (Irritating)]: Some of these materials may burn, but none ignite readily. Containers may explode when heated. (ERG, 2016)|Combustible. Gives off irritating or toxic fumes (or gases) in a fire.|Reactive - 1st degree
|Danger|H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P260, P264, P271, P273, P280, P284, P304+P340, P305+P351+P338, P310, P320, P337+P313, P403+P233, P405, and P501|H302 (74.51%): Harmful if swallowed [Warning Acute toxicity, oral]|P260, P264, P270, P271, P273, P280, P284, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P320, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 51 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P260, P261, P264, P270, P271, P280, P284, P301+P312, P302+P352, P304+P340, P305+P351+P338, P309+P311, P310, P312, P314, P320, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|P260, P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P307+P311, P311, P312, P314, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Excerpt from ERG Guide 159 [Substances (Irritating)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
Excerpt from ERG Guide 159 [Substances (Irritating)]: Do not touch or walk through spilled material. Stop leak if you can do it without risk. Fully encapsulating, vapor-protective clothing should be worn for spills and leaks with no fire. SMALL SPILL: Pick up with sand or other non-combustible absorbent material and place into containers for later disposal. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Prevent entry into waterways, sewers, basements or confined areas. (ERG, 2016)
Skin: Wear appropriate personal protective clothing to prevent skin contact. Eyes: Wear appropriate eye protection to prevent eye contact. Wash skin: The worker should immediately wash the skin when it becomes contaminated. Remove: Work clothing that becomes wet or significantly contaminated should be removed and replaced. Change: No recommendation is made specifying the need for the worker to change clothing after the work shift. (NIOSH, 2016)|If the use of respirators is necessary, the only respirators permitted are those that have been approved by the Mine Safety and Health Administration (formerly Mining Enforcement and Safety Administration) or by the National Institute for Occupational Safety and Health. ... Employees should be provided with and required to use impervious clothing, gloves, face shields (8-inch minimum), and other appropriate protective clothing necessary to prevent repeated or prolonged skin contact with liquid acetylene tetrabromide. ... Employees should be provided with and required to use splash-proof safety goggles where liquid acetylene tetrabromide may contact the eyes.|Because the vapor pressure /of acetylene tetrabromide/ is exceedingly low @ room temp, inhalation exposure may be controlled by reasonable precautions & ordinary ventilation.|Wear appropriate personal protective clothing to prevent skin contact.|Wear appropriate eye protection to prevent eye contact.|For more Personal Protective Equipment (PPE) (Complete) data for 1,1,2,2-TETRABROMOETHANE (7 total), please visit the HSDB record page.|(See protection codes)
Non combustible.
To fight a fire /involving/ acetylene tetrabromide use dry chemical, carbon dioxide, water-foam, or fog.|If material involved in fire: Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.)|Extinguish fire using agent suitable for surrounding fire. Use water spray to cool fire-exposed containers.
1. VENTILATE AREA OF SPILL OR LEAK. 2. COLLECT FOR RECLAMATION OR ABSORB IN VERMICULITE, DRY SAND, EARTH, OR A SIMILAR MATERIAL.|Stop or control the leak, if this can be done without undue risk. Use appropriate foam to blanket release and suppress vapors. Approach release from upwind. Absorb in noncombustible material for proper disposal. Control runoff and isolate discharged material for proper disposal.
Non-impervious clothing which becomes contaminated with liquid acetylene tetrabromide should be removed promptly and not reworn until the acetylene tetrabromide is removed from the clothing. Clothing wet with acetylene tetrabromide should be placed in closed containers for storage until it can be discarded or until provision is made for the removal of acetylene tetrabromide from the clothing. ... Skin that becomes contaminated with acetylene tetrabromide should be promptly washed or showered with soap or mild detergent and water to remove any acetylene tetrabromide.|SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|If material not involved in fire: Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.|Personnel protection: Avoid breathing vapors. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water.|For more Preventive Measures (Complete) data for 1,1,2,2-TETRABROMOETHANE (8 total), please visit the HSDB record page.
/GUIDE 159: SUBSTANCES (IRRITATING)/ Health: Inhalation of vapors or dust is extremely irritating. May cause burning of eyes and flow of tears. May cause coughing, difficult breathing and nausea. Brief exposure effects last only a few minutes. Exposure in an enclosed area may be very harmful. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause pollution.|/GUIDE 159: SUBSTANCES (IRRITATING)/ Fire or Explosion: Some of these materials may burn, but none ignite readily. Containers may explode when heated.|/GUIDE 159: SUBSTANCES (IRRITATING)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.|/GUIDE 159: SUBSTANCES (IRRITATING)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.|For more DOT Emergency Guidelines (Complete) data for 1,1,2,2-TETRABROMOETHANE (8 total), please visit the HSDB record page.
No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.
Prolonged or repeated contact ... might cause irritation of the skin.|An eye & skin irritant ... .
Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 1 ppm (14 mg/cu m).
After reviewing available published literature, NIOSH provided comments to OSHA on August 1, 1988, regarding the "Proposed Rule on Air Contaminants" (29 CFR 1910, Docket No. H-020). In these comments, NIOSH questioned whether the PEL proposed for acetylene tetrabromide [TWA 1 ppm] was adequate to protect workers from recognized health hazards.
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: self-contained breathing apparatus.
Separated from strong oxidants, strong bases and food and feedstuffs. Well closed. Ventilation along the floor.
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20 °C.
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system and liver. This may result in impaired functions.
The substance may have effects on the liver.
NO open flames.
PREVENT GENERATION OF MISTS!
Use ventilation, local exhaust or breathing protection.
Protective gloves.
Wear safety spectacles or eye protection in combination with breathing protection.
| 3 - Materials that, under emergency conditions, can cause serious or permanent injury.| 0 - Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand.| 1 - Materials that in themselves are normally stable but that can become unstable at elevated temperatures and pressures.
RURAL/REMOTE: 1,1,2,2-Tetrabromoethane was detected, not quantified in marine air samples collected over the western Pacific Ocean between 43 deg and 4 deg north during September, 1994(1).
Toxicity
highly toxic
Clioquinol at a dose of 30-50 mg/kg, demonstrated a weak antagonistic action with tetrabromoethane (80 mg/kg).
LD50 Rat oral 1200 mg/kg|LC50 Rat inhalation 549 mg/cu m/4 hr|LD50 Rat skin 5250 mg/kg|LD50 Mouse oral 269 mg/kg|For more Non-Human Toxicity Values (Complete) data for 1,1,2,2-TETRABROMOETHANE (7 total), please visit the HSDB record page.
1,1,2,2-Tetrabromoethane's production and use as a solvent and metal separator, in microscopy(1), flotation agent(2), and as a mercury substitute in gauges and balances(3) may result in its release to the environment through various waste streams(SRC).
TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 120(SRC), determined from a water solubility of 678 mg/l(3) and a regression-derived equation(4), indicates that 1,1,2,2-tetrabromoethane is expected to have high mobility in soil(SRC). Volatilization of 1,1,2,2-tetrabromoethane from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 1.34X10-5 atm-cu m/mole(SRC), derived from its vapor pressure, 0.02 mm Hg(2), and water solubility(3). The potential for volatilization of 1,1,2,2-tetrabromoethane from dry soil surfaces may exist(SRC) based upon its vapor pressure(2). 1,1,2,2-Tetrabromoethane, reached 29% of its theoretical BOD in 2 weeks using the Japanese MITI test(5), suggesting biodegradation in soil may be an important environmental fate process(SRC).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 120(SRC), determined from a water solubility of 678 mg/l(3) and a regression-derived equation(4), indicates that 1,1,2,2-tetrabromoethane is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(4) based upon an estimated Henry's Law constant of 1.34X10-5 atm-cu m/mole(SRC), derived from its vapor pressure, 0.02 mm Hg(2), and water solubility, 678 mg/l(3). Using this Henry's Law constant and an estimation method(4), volatilization half-lives for a model river and model lake are 5 and 43 days, respectively(SRC). However, hydrolysis half-lives of 20 and 2 hours at pH 7 and 8, respectively, have been calculated(5); therefore, under acidic or neutral conditions, hydrolysis will be the dominant removal process(SRC). According to a classification scheme(6), a BCF of <8.2(7), suggests that bioconcentration in aquatic organisms is low(SRC). A theoretical BOD of 29% was reported using an activated sludge inoculum at 30 mg/l and the Japanese MITI test over a 2 week test period(7), suggesting that biodegradation may occur in aquatic systems(SRC).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 1,1,2,2-tetrabromoethane, which has a vapor pressure of 0.02 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 1,1,2,2-tetrabromoethane is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 115 days(SRC), calculated from its rate constant of 1.4X10-13 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3).
The rate constant for the vapor-phase reaction of 1,1,2,2-tetrabromoethane with photochemically-produced hydroxyl radicals has been estimated as 1.4X10-13 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 115 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Hydrolysis will be the dominant environmental fate process for 1,1,2,2-tetrabromoethane under neutral or basic conditions(3). A base-catalyzed second-order hydrolysis rate constant for this compound is 96.5 L/mole-sec(2); this corresponds to half-lives of 20 and 2 hours at pH values of 7 and 8, respectively(2).
5.50|BCF values of <8.2 and 0.5 to 7 were measured for 1,1,2,2-tetrabromoethane at compound concns of 1 ug/l and 10 ug/l, respectively(1). According to a classification scheme(2), these values BCF suggest that bioconcentration in aquatic organisms is low(SRC).
The Koc of 1,1,2,2-tetrabromoethane is estimated as 120(SRC), using a water solubility of 678 mg/l(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 1,1,2,2-tetrabromoethane is expected to have high mobility in soil(SRC).
The Henry's Law constant for 1,1,2,2-tetrabromoethane is estimated as 1.3X10-5 atm-cu m/mole(SRC) derived from its vapor pressure, 0.02 mm Hg(1), and water solubility, 678 mg/l(2). This Henry's Law constant indicates that 1,1,2,2-tetrabromoethane is expected to volatilize from water surfaces(3). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(3) is estimated as 5 days(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(3) is estimated as 43 days(SRC). 1,1,2,2-Tetrabromoethane's estimated Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). The potential for volatilization of 1,1,2,2-tetrabromoethane from dry soil surfaces may exist(SRC) based upon its vapor pressure(1).
NIOSH (NOES Survey 1981-1983) has statistically estimated that 2,516 workers are potentially exposed to 1,1,2,2-tetrabromoethane in the US(1). Occupational exposure to 1,1,2,2-tetrabromoethane may occur through inhalation and dermal contact with this compound at workplaces where 1,1,2,2-tetrabromoethane is produced or used(SRC).
Drug Information
1,1,2,2-Tetrabromo[U-14C]ethane ([14C]TBE) was used to study the metabolism of TBE in rats. Three graded doses of TBE (1.17, 13.6, and 123 mg/kg; 1 microCi 14C/rat at each dose) were administered by gavage to three groups of four rats each. Excreta samples were collected at various time intervals up to 96 hr. Following euthanization, 14C activity was measured in the excreta, tissues, and carcass. The fraction of the dose exhaled as volatile metabolites of TBE, excluding 14CO2, was approximately 9-10% higher in rats given the high dose of TBE compared to that in rats given either the low or the medium dose. The fraction excreted in the urine decreased with increasing TBE dosage. 1,2-Dibromoethylene and tribromoethylene were identified as exhaled metabolites at the high dose. Three major urinary metabolites were identified: dibromoacetic acid, glyoxylic acid, and oxalic acid. The results of this study indicate that the metabolism of TBE was linear up to a dose of 13.6 mg/kg, but the contribution of various TBE metabolic pathways was different at a dose of 123 mg/kg.
Excerpt from ERG Guide 159 [Substances (Irritating)]: Inhalation of vapors or dust is extremely irritating. May cause burning of eyes and flow of tears. May cause coughing, difficult breathing and nausea. Brief exposure effects last only a few minutes. Exposure in an enclosed area may be very harmful. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may cause pollution. (ERG, 2016)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)|(See procedures)
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Aliphatic hydrocarbons and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory rest. Positive pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Aliphatic hydrocarbons and related compounds/|Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Anticipate seizures and treat if necessary ... . Use rapid rewarming techniques if frostbite occurs ... . /Simple ashpyxiants and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Treat seizures with diazepam ... . /Simple ashpyxiants and related compounds/
... CHEMIST WORKING FOR 7.5 HR IN 1-2 PPM TBE /1,1,2,2-TETRABROMOETHANE/ WITH SINGLE 10 MIN EXPOSURE TO ABOUT 16 PPM WAS HOSPITALIZED FOR 9 WEEKS WITH NEAR-FATAL LIVER INJURY WHICH DEVELOPED OVER SEVERAL DAYS. HIS INITIAL SYMPTOMS WERE HEADACHE, ANOREXIA, VOMITING, AND STOMACH PAINS. BY THE FIFTH DAY AFTER EXPOSURE, ICTERUS, UROBILINURIA, BILIRUBINURIA, AND MONOCYTOSIS WERE APPARENT.|CONTACT WITH SKIN (AS IN BOOTS, SHOES, & UNDERCLOTHES) CAN CAUSE BLISTERING.|Acetylene tetrabromide may cause eye and nose irritation, headache, loss of appetite, nausea, abdominal pain, kidney and liver damage with such symptoms as dark urine and yellow jaundice. Breathing high concentrations of this chemical might damage the lung.|CAUTION: IRRITANT ... /CNS DEPRESSANT/|An individual with acute tetrabromoethane exposure was evaluated with positron emission tomography (PET), topographical electroencephalogram (EEG), and neurobehavioral assessment. Results suggest widespread central nervous system (CNS) dysfunction consistent with a solvent-induced encephalopathy.
1,1,2,2-tetrabromoethane
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.|inhalation, ingestion, skin and/or eye contact
irritation eyes, nose; anorexia, nausea; headache; abdominal pain; jaundice; leukocytosis (increased blood leukocytes); central nervous system depression
Cough. Sore throat. Headache. Dizziness. Nausea. Abdominal pain.
Redness.
Redness.
Eyes, respiratory system, liver, central nervous system
1,1,2,2-Tetrabromoethane Use and Manufacturing
From the addition of acetylene and bromine. Add bromine to the glass-lined reaction pot and add a small amount of water to close the bromine liquid surface. Then, the acetylene gas was slowly introduced from the liquid, maintained at 58-62°C, and aerated for 5-7 hours under the condition of 0.02-0.05MPa, and the reaction was stopped after the reaction liquid gradually turned yellow. The reaction solution was washed with dilute sodium carbonate solution, then washed with water to neutrality, and the washing water was separated to obtain the finished product of tetrabromoethane. Raw material consumption quota: bromine 1110kg/t, calcium carbide 1940kg/t.
In microscopy, as solvent, separating minerals by density.
(1977) AT LEAST 4.54X10+8 G|(1982) PROBABLY GREATER THAN 2.27X10+6 G
Grades: Technical|Purity: Not less than 98%
Ethane, 1,1,2,2-tetrabromo-: ACTIVE|Method of purification: rectification.
NIOSH Method 2003. Determination of 1,1,2,2-Tetrabromoethane by Gas Chromatography with Flame Ionization Detection. Workplace. Detection limit = 0.800 mg/cu m.
Fire Hazards -> Reactive - 1st degree
Computed Properties
Molecular Weight:345.65
XLogP3:3.6
Rotatable Bond Count:1
Exact Mass:345.68490
Monoisotopic Mass:341.68900
Heavy Atom Count:6
Complexity:26.5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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6-CHLORO-3-PHENYL-2-QUINOLINOL Formula
85274-64-2
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2,5-Furandione, dihydro-, monopolyisobutylene derivs. Formula
67762-77-0
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N-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoroundecyl)maleimide Structure
852527-40-3
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2-Benzothiazolecarboxaldehyde,5-methoxy-(5CI) Structure
854059-90-8
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What is Benzamide, 5-(aminosulfonyl)-N-[(2-ethyloctahydro-1H-isoindol-1-yl)methyl]-2-methoxy-, hydrochloride (1:1)
85409-39-8
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What is 3-(2,4-Dimethylphenyl)-5-phenyl-1H-1,2,4-triazole
85303-90-8