Ethyl 1-methyl-3-piperidinecarboxylate
-
Ethyl 1-methyl-3-piperidinecarboxylate
structure -
-
CAS No:
5166-67-6
-
Formula:
C9H17NO2
-
Chemical Name:
Ethyl 1-methyl-3-piperidinecarboxylate
-
Synonyms:
3-Piperidinecarboxylic acid,1-methyl-,ethyl ester;Nipecotic acid,1-methyl-,ethyl ester;Ethyl 1-methyl-3-piperidinecarboxylate;Ethyl 1-methylnipecotate;Ethyl N-methylnipecotate;NSC 64739
- Categories:
-
CAS No:
Characteristics
29.5
1
Clear colorless to pale yellow liquid
0.981 g/cm3 @ Temp: 20 °C
105-107 °C @ Press: 2.5 Torr
155 °F
1.459
Safety Information
NONH for all modes of transport
3
36/37/38
26-36/37/39-37/39
Xi
Irritant
P261-P305 + P351 + P338
H315-H319-H335
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Ethyl 1-methyl-3-piperidinecarboxylate Use and Manufacturing
General procedure: An autoclave was filled with catalyst (1 molpercent based on the molar amount of amine), flushed with argon and topped up with a solution of amine (0.1 mol) and orthocarboxylic acid ester (0.11-0.3mol) in 10 ml of methanol (or ethanol) and 0.5 ml of a 0.2 M solution of anhydrous ptoluenesulphonic acid in methanol (or ethanol). The mixture was heated to 120°C and hydrogen was injected to 40 bar and then the mixture was stirred at a constant pressure until hydrogen absorption could no longer be detected (0.2 - 6 h). After being filtered off from the catalyst, the filtrate was distilled.
Computed Properties
Molecular Weight:171.24
XLogP3:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:171.125928785
Monoisotopic Mass:171.125928785
Topological Polar Surface Area:29.5
Heavy Atom Count:12
Complexity:159
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Learn More Other Chemicals
-
Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, ethyl ester, (1alpha,3R,4alpha,5R)- (9CI)
463325-95-3
-
Cyclopropanecarboxylic acid, 1-formyl-2-methyl-, ethyl ester (9CI)
260261-27-6
-
3-CYCLOPROPYL-2-METHYL-3-OXO-PROPIONIC ACID ETHYL ESTER
21741-37-7
-
Cyclopropanecarboxylic acid, 1-amino-2-phenyl-, ethyl ester, (1R,2R)-rel- (9CI) Formula
669058-57-5
-
Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester, (1R,2S)-rel- (9CI) Formula
213316-32-6
-
Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester, hydrochloride (9CI) Formula
681807-60-3
-
3-Cyclopentene-1-carboxylic acid, 1-(chlorocarbonyl)-, ethyl ester (9CI) Structure
76910-09-3
-
Cyclopropanecarboxylic acid, 2-propyl-, ethyl ester, (1R,2S)- (9CI) Structure
492468-18-5
-
What is Cyclopentanecarboxylic acid, 2-(formylhydrazono)-, ethyl ester, (Z)- (9CI)
163352-99-6
-
What is 2-[(2,6-Dichlorophenyl)sulfonyl]acetic acid ethyl ester
1154228-17-7
Ethyl 1-methyl-3-piperidinecarboxylate
SDSRequest for Quotation